N-Acyamino Acid Thickening Agent for Oily Bases
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Solution Overview
Problem
Existing thickening agents for oily bases, such as polyamide resin and acylamino acids, are limited in their ability to thicken a wide variety of oily agents, often resulting in unsatisfactory gel compositions that are not smooth when applied to the skin and require high temperatures for dissolution, leading to comfort and solubility issues.
Innovation Solution
A thickening agent comprising a specific N-acylamino acid and amideamine, represented by formula (I), which can thicken a wide range of oily bases including hydrocarbon oil and silicone, producing a creamy composition with a practical dissolution temperature and smooth skin application.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Adaptability or versatility
If conventional thickening agents (polyamide resin, acylamino acid, amine salt) are used, then thickening of specific oily agents is achieved, but the ability to thicken a wide variety of oily agents is limited
Solution Approach 1:
The patent develops a thickening agent with universal applicability to multiple oily base types (hydrocarbon oil, ester oil, silicone oil) by designing a composite system that can adapt to different oil chemistries, eliminating the need for different thickening agents for different oil types
Solution Approach 2:
The invention uses a composite thickening system comprising N-acylamino acid, amideamine, and optionally fatty acid, where the synergistic interaction between components enables broad compatibility with various oily bases while maintaining reliable thickening performance
2Reliability
If acylamino acid amine salt is used as gelatinizing agent, then gelatinizing capability is enhanced by combining with waxes, but the number of components and complexity increases
Solution Approach 1:
The patent combines multiple thickening components (N-acylamino acid, amideamine, and optionally fatty acid) into a single integrated thickening system that provides both thickening and gelatinizing capabilities without requiring separate wax additives, simplifying the overall formulation
Solution Approach 2:
The composite thickening agent performs multiple functions (thickening, gelatinizing, stabilizing) simultaneously, replacing the need for multiple separate additives and reducing formulation complexity while maintaining or enhancing gelatinizing capability
3Adaptability or versatility
If N-acyl-L-glutamic acid dibutylamide is used as gelatinizing agent, then various oily agents can be gelatinized, but high dissolution temperature (about 150°C) is required
Solution Approach 1:
The patent modifies the chemical structure and composition of the thickening system (using N-acylamino acid combined with amideamine) to change the dissolution temperature parameter from high (150°C) to a more practical range, while preserving the ability to gelatinize various oily agents
4Reliability
If conventional thickening agents are used, then thickening is achieved, but the obtained composition is not smooth when applied to skin
Solution Approach 1:
The patent optimizes the local quality of the thickening composition by selecting specific components (N-acylamino acid, amideamine, fatty acid) that provide both thickening performance and smooth skin feel, creating a composition with differentiated properties for both functions
Data Source
AI summary
Thickening agents which containing a specific N-acylamino acid (component A) and a specific amideamine (component B) are capable of generating, when used in combination with a wide variety of oily bases including a hydrocarbon oil and silicone, a creamy thickening composition having a practical dissolution temperature and a smooth feeling in use when applied to the skin.

