Thioamide Herbicides Resolving Crop Compatibility Contradictions
Find Innovative SolutionsGenerate Solutions
Solution Overview
Problem
Current herbicides based on N-(tetrazol-5-yl)- and N-(triazol-5-yl)nicotinamides are not sufficiently active against broad-leaved weeds and are incompatible with certain crop species like cereals and rice.
Innovation Solution
Development of N-(tetrazol-5-yl)- and N-(triazol-5-yl)arylcarboxylic acid thioamides, which differ from prior art due to their thioamide structure, offering enhanced herbicidal activity and compatibility with various crops.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If N-(tetrazol-5-yl)- and N-(triazol-5-yl)nicotinamides are used as herbicides, then herbicidal activity is provided, but sufficient activity against broad-leaved weeds is not achieved and compatibility with certain crop species is insufficient
Solution Approach 1:
The patent applies parameter changes by modifying the chemical structure of the herbicide compound - specifically replacing the nicotinamide core with arylcarboxylic acid thioamide structures containing tetrazole or triazole groups. This structural parameter change results in compounds that maintain herbicidal activity while improving compatibility with broad-leaved crops and cereals, thus resolving the contradiction between herbicidal efficacy and crop safety
Solution Approach 2:
The invention creates composite molecular structures by combining tetrazole or triazole groups with arylcarboxylic acid thioamide frameworks. This composite approach generates new chemical entities that exhibit both the desired herbicidal properties and improved selectivity toward specific crop species, addressing the limitations of the parent nicotinamide compounds
2Productivity
If existing herbicide structures are used, then broad spectrum weed control is provided, but damage to economically important crops occurs
Solution Approach 1:
The patent employs local quality by introducing specific functional groups (tetrazole or triazole) at particular positions on the arylcarboxylic acid thioamide structure. This localized structural modification confers selective toxicity - the compounds maintain effectiveness against broad-leaved weeds while exhibiting reduced phytotoxicity to economically important crops, thus achieving both weed control and crop protection
Data Source
AI summary
N-(Tetrazol-5-yl)- and N-(triazol-5-yl)arylcarboxylic acid thioamides of the general formula (I) are described as herbicides.In this formula (I), R, W, X and Z represent radicals such as hydrogen, organic radicals such as alkyl, and other radicals such as halogen. A and B each represent carbon or nitrogen.