Three-Component MSM and FDP Regimens to Reduce Supplement Interference

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Solution Overview

Problem

The cancellation and interference effects among multiple nutritional supplements diminish their beneficial effects due to overlapping, opposing, and unprincipled combinations, leading to reduced bioavailability and hindered synergy.

Innovation Solution

The Nutritional Supplement Treatment Regimen (NSTR™) involves the serial and cumulative administration of multiple nutritional supplements at different times to minimize cancellation and interference, ensuring maximum benefit with minimal adverse effects.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Quantity of substance

If multiple nutritional supplements are taken simultaneously or randomly, then the quantity of substances increases, but cancellation and interference effects occur that diminish beneficial effects and reduce bioavailability

Engineering Contradiction:

Improvequantity of nutritional supplementsVSAvoidbeneficial effects

Core Design Contradiction:

Quantity of substanceVSReliability

Solution Approach 1:

The patent divides nutritional supplements into separate dosage forms or time intervals rather than administering all supplements simultaneously. This segmentation prevents cancellation and interference effects by ensuring that supplements with opposing or similar effects do not interact negatively, thereby maintaining reliable beneficial effects while still providing multiple nutritional substances.

Inventive Principle:

Principle #1Segmentation

2Adaptability or versatility

If multiple nutritional supplements with overlapping or opposing effects are combined, then the variety of substances increases, but the beneficial effects cancel each other out

Engineering Contradiction:

Improvevariety of nutritional supplementsVSAvoidbeneficial effects

Core Design Contradiction:

Adaptability or versatilityVSReliability

Solution Approach 1:

The patent applies local quality by assigning specific characteristics to different supplement combinations or time periods. Supplements with complementary effects are grouped together, while those with opposing effects are separated in time or formulation. This ensures that each local combination maintains reliable beneficial effects without cancellation, while the overall regimen provides diverse nutritional coverage.

Inventive Principle:

Principle #3Local quality

3Ease of operation

If nutritional supplements are administered without considering timing and interactions, then the ease of operation increases, but cancellation and interference effects reduce overall effectiveness

Engineering Contradiction:

Improveease of supplement administrationVSAvoidbeneficial effects

Core Design Contradiction:

Ease of operationVSReliability

Solution Approach 1:

The patent implements periodic action by scheduling nutritional supplement administration at specific time intervals rather than continuously or randomly. This periodic timing allows the body to process and respond to each supplement effectively, preventing cancellation and interference effects while maintaining ease of operation through a structured but simple dosing schedule.

Inventive Principle:

Principle #19Periodic action

Data Source

PatentUS12383485B1Multi-component nutritional supplement formulations and treatment regimen

Publication Date: 2025.08.12 ROSEN GENE S

AI summary

Multi-component pharmaceutical compositions perform various functions and confer various benefits by providing methylsulfonylmethane (MSM), fructose diphosphate (FDP), and an herbal component or a nutritional component. Compositions adhering to that pattern have unique and beneficial properties. Such compositions contain only three active components, in order to avoid canceling the positive effects of such compositions when too many components are present. The present claims expand on the work patented in U.S. Pat. Nos. 9,682,048 B1, 10,166,267 B1, and 10,183,053 B1.