Three-Layer Aqueous Patch Backing for Moisture Control
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Solution Overview
Problem
Aqueous patches face challenges in maintaining adhesive power and controlling moisture evaporation, leading to issues like cohesive failure and skin irritation due to high moisture permeability or blockage, and existing solutions fail to stabilize water content and drug efficacy over time.
Innovation Solution
A three-layer backing structure comprising an inner fiber layer, a film layer with through-holes for controlled water evaporation, and an air-permeable outer fiber layer, which stabilizes moisture and prevents liquid exudation, ensuring appropriate water content and prolonged adhesive power.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Ease of operation
If a woven fabric or nonwoven fabric is used as a backing, then air permeability is improved, but water evaporation is excessive causing hardening of the pasty preparation and decrease of adhesive power
Solution Approach 1:
The backing is divided into three distinct layers: an inner fiber layer for holding the pasty preparation, a film layer with through-holes for controlled water evaporation, and an outer fiber layer for breathability. This segmentation allows each layer to perform its specific function, preventing both excessive moisture loss and liquid exudation.
Solution Approach 2:
The invention uses a composite structure combining different materials (fibers and film) with specific properties. The film layer provides moisture control while the fiber layers provide breathability and holding capacity, creating a composite backing that balances multiple competing requirements.
2Reliability
If a film such as plastic is used as a backing, then water evaporation is blocked, but liquid exudate accumulates causing cohesive failure and decrease of adhesiveness
Solution Approach 1:
The film layer is designed with through-holes that allow controlled passage of water vapor while blocking liquid exudate. This porous structure enables selective permeability based on the physical state of the substance, preventing liquid accumulation while maintaining moisture control.
Solution Approach 2:
Different regions of the backing have different properties: the film layer provides liquid barrier function while the fiber layers provide breathability. This local differentiation of material properties allows the backing to simultaneously prevent liquid exudate accumulation and control water evaporation.
3Reliability
If through-holes are formed in the film to control moisture, then water evaporation is regulated, but fat components permeate the film causing wrinkles and kinks
Solution Approach 1:
The inner fiber layer is positioned to hold the pasty preparation before it can contact the film layer. This preliminary containment prevents fat components from permeating the film and causing deformation, while still allowing the film's through-holes to regulate water evaporation effectively.
4Ease of operation
If a two-layer structure is used to control moisture permeability, then air permeability is adjusted, but moisture control is insufficient for hard pasty preparations with low liquid content
Solution Approach 1:
The invention transitions from a two-layer to a three-layer structure, adding the inner fiber layer dimension. This additional layer provides a dedicated interface for holding hard pasty preparations, ensuring sufficient moisture control through enhanced capillary action and surface area contact.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The solution effectively maintains skin moisture, prevents peeling, and ensures long-term therapeutic effects by stabilizing water content and drug release, while preventing residue and skin irritation.
Implementation Method 1
a film layer having through-holes for controlling the water evaporation
Implementation Method 2
an air-permeable outer fiber layer which prevents leaking out of the pasty preparation or a liquid component exuded from the pasty preparation
Data Source
AI summary
The present invention relates to a backing having a three-layer structure prepared by sticking together an inner fiber layer for holding a pasty preparation, a film layer having through-holes, and an air-permeable outer fiber layer which prevents leaking out of the pasty preparation or a liquid component exuded from the pasty preparation, and also relates to an aqueous patch using the backing which can be applied for a long time.