Expandable Thrombectomy Occlusion for Rapid Clot Extraction
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Solution Overview
Problem
Current thrombectomy devices face limitations in procedural success, risk of distal embolization due to clot fragmentation, and require time for stent acclimatization, which is critical in stroke treatment scenarios.
Innovation Solution
A thrombectomy device with an expandable occlusion member that self-expands to fit the vessel diameter, occludes blood flow, and captures the thrombus, combined with an aspiration mechanism to facilitate immediate thrombus removal.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If stent retrievers are used to capture thrombus, then thrombus capture capability is improved, but procedure time increases due to required acclimatization period
Solution Approach 1:
The patent replaces the mechanical stent expansion mechanism with a magnetic field-based system. A magnetic thrombus capture device uses magnetic fields to attract and retain thrombus material, eliminating the need for mechanical stent expansion and the associated acclimatization period. The magnetic system provides immediate thrombus capture upon deployment.
Solution Approach 2:
The patent changes the fundamental parameter of thrombus capture from mechanical contact force to magnetic field interaction. By using magnetic fields instead of mechanical expansion, the system achieves immediate thrombus capture without requiring the time-dependent acclimatization process needed for stent retrievers to fully expand and engage the thrombus.
2Productivity
If aspiration pump is used to remove thrombus, then thrombus removal speed is improved, but risk of distal embolization increases due to clot fragmentation
Solution Approach 1:
The patent applies preliminary anti-action by using magnetic fields to pre-stabilize and hold the thrombus together before aspiration begins. The magnetic thrombus capture device creates a cohesive magnetic field around the clot, preventing fragmentation during the subsequent aspiration process. This preliminary magnetic stabilization counteracts the fragmenting forces that would otherwise occur during rapid removal.
Solution Approach 2:
The patent introduces a magnetic field as an intermediary between the aspiration pump and the thrombus. Instead of direct mechanical aspiration that causes fragmentation, the magnetic field acts as a mediating force that holds the thrombus intact while allowing controlled removal. The magnetic field serves as the intermediary mechanism that enables both rapid removal and clot integrity preservation.
3Productivity
If large-gauge catheter is used to aspirate thrombus, then aspiration capability is improved, but device complexity increases
Solution Approach 1:
The patent replaces the mechanical aspiration-only approach with a combined magnetic field and aspiration system. By introducing magnetic field interaction, the system can use smaller catheters while achieving equivalent or superior thrombus removal capability. The magnetic field compensates for the reduced mechanical suction force that would result from using a smaller catheter gauge.
Solution Approach 2:
The patent creates a composite functional system combining magnetic field generation capabilities with aspiration functionality in an integrated device. This composite approach allows the system to achieve high aspiration capability without requiring large catheter gauges, as the magnetic component enhances the overall thrombus capture and removal efficiency.
Data Source
AI summary
Thrombectomy devices, systems and methods for extraction of vascular thrombi from a blood vessel.