Intermittent Thrombus Aspiration Pump for High Pressure-Difference Suction
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Solution Overview
Problem
Existing thrombus aspiration devices struggle to effectively remove hardened and fibrotic thrombi without causing excessive blood loss by increasing negative pressure, which leads to clinical complications.
Innovation Solution
An intermittent suction thrombus aspiration pump system with a suction catheter, flow resistor, pressure sensors, metering pump, clamp valve, and negative pressure regulating valve, which creates a controlled pressure difference to intermittently aspirate thrombi, enhancing thrombus removal without increasing negative pressure.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Productivity
If negative pressure is increased to extract hardened and fibrotic thrombi, then thrombus removal effectiveness is improved, but blood loss increases excessively
Solution Approach 1:
The patent implements intermittent aspiration by periodically switching the aspiration pump on and off. During the on-phase, negative pressure is applied to remove thrombi; during the off-phase, pressure equalizes to minimize blood loss. This periodic action allows effective thrombus extraction while controlling blood loss through rhythmic pressure application.
Solution Approach 2:
The system dynamically adjusts the negative pressure levels and aspiration duration based on real-time feedback from flow sensors and pressure sensors. The control unit modifies pump operation parameters to optimize thrombus removal effectiveness while preventing excessive blood loss, making the pressure application adaptive rather than static.
2Power
If negative pressure is increased to remove thrombi, then aspiration power is improved, but blood extraction increases excessively
Solution Approach 1:
The system incorporates flow sensors and pressure sensors that provide real-time feedback to the control unit. When blood flow rate or pressure reaches predetermined thresholds indicating excessive blood extraction, the control unit automatically adjusts or stops the aspiration pump, thereby maintaining effective thrombus removal while preventing excessive blood loss.
Solution Approach 2:
By implementing intermittent aspiration cycles with controlled duration and intensity, the system delivers high-power aspiration bursts to remove thrombi effectively, then allows pressure equalization periods to minimize blood extraction, achieving high aspiration power without proportionally increasing blood loss.
3Duration of action of stationary object
If continuous aspiration is maintained, then thrombus removal continuity is improved, but blood loss accumulates excessively
Solution Approach 1:
The system replaces continuous aspiration with periodic intermittent aspiration cycles. Each cycle includes an aspiration phase for thrombus removal and a pause phase for pressure equalization. This maintains overall treatment duration and thrombus removal continuity while significantly reducing cumulative blood loss through rhythmic interruption.
Solution Approach 2:
The aspiration process is made dynamic through real-time monitoring and adjustment of pump operation. The system adapts the duration and intensity of aspiration phases based on thrombus characteristics and blood loss feedback, maintaining effective continuous treatment while dynamically controlling blood loss accumulation.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The system effectively aspirates stubborn thrombi by creating a high-pressure difference momentarily, reducing blood loss and ensuring rapid thrombus extraction.
Implementation Method 1
a negative pressure pump (10), wherein the suction catheter (1), the first pressure sensor (4), the flow resistor (2), the second pressure sensor (3), the clamp valve (6), the collection container (7), the third pressure sensor (8), the negative pressure regulating valve (9), and the negative pressure pump (10) are connected in sequence
Implementation Method 2
the flow resistor (2) is located between the first pressure sensor (4) and the second pressure sensor (3), so that when blood flows, a pressure difference is generated between the first pressure sensor (4) and the second pressure sensor (3), and the pressure difference is proportional to a blood flow rate
Implementation Method 3
the metering pump generates a liquid flow direction during working and discharges a liquid on one side of the clamp valve to the other side, thereby generating a larger pressure difference
Data Source
AI summary
An intermittent suction thrombus aspiration pump system includes: a suction catheter, a flow resistor, a first pressure sensor, a second pressure sensor, a metering pump, a clamp valve, a collection container, a third pressure sensor, a negative pressure regulating valve, and a negative pressure pump. The suction catheter, the first pressure sensor, the flow resistor, the second pressure sensor, the clamp valve, the collection container, the third pressure sensor, the negative pressure regulating valve, and the negative pressure pump are connected in sequence. Two ends of the metering pump are respectively connected to two ends of the clamp valve. The intermittent suction thrombus aspiration pump system can actively increase the pressure difference without increasing the negative pressure output by the negative pressure pump, thereby achieving the purpose of instantly sucking thrombus.