Thrombus Extraction Device Coring and Net Capture Mechanism
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Solution Overview
Problem
Current methods for treating deep vein thrombosis (DVT) are inadequate due to high recurrence rates, inability to effectively remove large clot volumes, and complex treatment procedures involving multiple devices and pharmaceuticals.
Innovation Solution
A thrombus extraction device comprising a self-expanding coring portion connected to a braided net that cores and separates large clot volumes from vessels, reducing the need for thrombolytics and minimizing bleeding risks and recovery time.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Productivity
If current DVT treatment methods are used, then treatment can be provided, but high recurrence rates and inability to remove large clot volumes occur
Solution Approach 1:
The device extracts thrombus directly from the vessel using a combination of coring and net capture mechanisms. The coring portion mechanically removes the core of the thrombus while the braided net captures fragmented clot material, enabling effective removal of large clot volumes and reducing recurrence rates.
Solution Approach 2:
The thrombus extraction device is divided into functional segments: a coring portion for removing thrombus core and a braided net portion for capturing fragmented clot. This segmentation allows each component to perform its specific function optimally, improving overall clot removal efficiency.
2Productivity
If thrombolytic pharmaceuticals are used extensively, then clot dissolution can occur, but bleeding risk increases
Solution Approach 1:
The device replaces chemical thrombolysis with mechanical thrombus removal through coring and net capture. This mechanical approach achieves effective clot removal without the systemic bleeding risks associated with thrombolytic pharmaceuticals, as the mechanical action is localized to the thrombus itself.
3Adaptability or versatility
If multiple treatment devices and pharmaceuticals are used, then comprehensive treatment can be provided, but treatment complexity increases
Solution Approach 1:
The device merges multiple functions into a single integrated system: the coring portion for mechanical thrombus removal, the braided net for fragment capture, and the delivery catheter for minimally invasive access. This consolidation provides comprehensive treatment capability while reducing the number of separate devices and pharmaceuticals needed.
4Quantity of substance
If large clot volumes are attempted to be removed, then more thrombus can be extracted, but device complexity increases
Solution Approach 1:
The thrombus extraction device employs a nested structure where the coring portion is positioned within the braided net, and both are contained within a delivery catheter. This nested design allows the device to maintain a compact profile for easy delivery while providing the capacity to extract large clot volumes through the combined action of its nested components.
Data Source
AI summary
Systems and methods for removal of thrombus from a blood vessel in a body of a patient are disclosed herein. The method can include: providing a thrombus extraction device including a proximal self-expanding member formed of a unitary fenestrated structure, a distal substantially cylindrical portion formed of a net-like filament mesh structure, and an inner shaft member connected to a distal end of the net-like filament mesh structure; advancing a catheter constraining the thrombus extraction device through a vascular thrombus, deploying the thrombus extraction; retracting the thrombus extraction device to separate a portion of the thrombus from the vessel wall and to capture the portion of the thrombus within the net-like filament mesh structure; and withdrawing the thrombus extraction device from the body to remove thrombus from the patient.


