Thrombus Treatment Platform with Expandable Stirrer

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Solution Overview

Problem

Existing thrombus removal devices are complex, costly, and can damage blood vessel endothelium, leading to sequelae such as bleeding and hemolysis.

Innovation Solution

A thrombus treatment platform comprising an aspiration catheter with a filter assembly and a stirring device, which includes a stirrer that can be expanded and collapsed to scrape the blood vessel wall and break thrombi without damaging the vessel.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If a spiral cutter is used to cut and remove thrombus, then thrombus removal capability is improved, but blood vessel endothelium damage increases

Engineering Contradiction:
Improvethrombus removal capabilityVSAvoidblood vessel endothelium damage
Core Design Contradiction:
ProductivityVSObject-affected harmful factors

Solution Approach 1:

The patent replaces the mechanical spiral cutter with a catheter-based aspiration system that uses a balloon to compress and remove thrombus. This substitution eliminates the mechanical cutting action that damages the endothelium while maintaining effective thrombus removal through compression and suction.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The patent introduces a balloon as an intermediary element between the catheter and thrombus. The balloon compresses the thrombus for removal while the catheter wall protects the blood vessel endothelium from direct contact with cutting mechanisms, thus removing thrombus without damaging the vessel lining.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Productivity

If high-pressure rapid stirring is used to break thrombus, then thrombus breakdown efficiency is improved, but red blood cell damage and hemolysis increase

Engineering Contradiction:
Improvethrombus breakdown efficiencyVSAvoidred blood cell damage and hemolysis
Core Design Contradiction:
ProductivityVSObject-generated harmful factors

Solution Approach 1:

The patent replaces high-pressure rapid stirring with a controlled compression mechanism using a balloon. This substitution achieves thrombus breakdown through gradual compression and aspiration rather than violent mechanical agitation, thereby preventing red blood cell damage and hemolysis while maintaining breakdown efficiency.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

3Productivity

If long negative pressure time is used for thrombus aspiration, then thrombus removal completeness is improved, but blood loss increases

Engineering Contradiction:
Improvethrombus removal completenessVSAvoidblood loss
Core Design Contradiction:
ProductivityVSLoss of substance

Solution Approach 1:

The patent employs continuous compression and aspiration action through the balloon mechanism, maintaining steady negative pressure throughout the procedure. This continuous action ensures complete thrombus removal while the controlled nature of the compression prevents excessive blood loss that would occur with prolonged or intermittent negative pressure application.

Inventive Principle:
Principle #20Continuity of useful action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The platform effectively removes thrombi while protecting the blood vessel wall, reducing the risk of sequelae and allowing for quick and safe removal of deep vein thrombi and old thrombi.

Implementation Method 1

a stirrer arranged at the distal end of the first catheter and having an expanded state and a collapsed state

Methodology Applied
Scientific EffectFriction: Friction

Implementation Method 2

the stirrer can be switched between the expanded state and the collapsed state by causing the first catheter and the second catheter to slide relatively

Methodology Applied
Scientific EffectMechanical Force: Mechanical Force

Implementation Method 3

a filter assembly, The filter assembly comprises a filter rod, and a filter screen fixedly mounted at the distal end of the filter rod

Methodology Applied
Scientific EffectFiltration: Filter (physical)

Implementation Method 4

an aspiration pump that communicate with the proximal end of the aspiration catheter

Methodology Applied
Scientific EffectSuction: Suction

Data Source

PatentUS12303161B2Thrombus treatment platform
Publication Date: 2025.05.20 SUZHOU TIANHONGSHENGJIE MEDICAL INSTR CO LTD
  • US12303161B2 patent drawing
  • US12303161B2 patent drawing
  • US12303161B2 patent drawing

AI summary

A thrombus treatment platform comprises an aspiration catheter, an aspiration pump, a stirring device and a filter assembly, the filter assembly comprises a filter rod and a filter screen; the stirring device comprises a first catheter, a second catheter, a stirrer and an operating device capable of causing the first catheter and the second catheter to slide relatively so that the stirrer can be switched between the expanded state and the collapsed state; the thrombus treatment platform further comprises a driving device capable of driving the rotation of the stirrer. The present disclosure can remove thrombus under the condition of ensuring relative safety, and is particularly suitable for removing a large number of thrombus in the inferior vena cava, protects venous valves and venous vessel walls, has controllable blood loss and simple operation steps, shortens operation time, and reduces patient hospitalization expenses.