Multi-Site Through-Hole Sensor Assembly for Wide Dynamic Range
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Solution Overview
Problem
Existing biological and chemical sensors face challenges in achieving high selectivity, sensitivity, and speed of measurement, particularly in quantifying analytes over a wide range of concentrations, often requiring a trade-off between sensitivity and dynamic range, and suffering from long equilibration times.
Innovation Solution
A sensor assembly with plural sensing sites, each having distinct through hole configurations, provides measurement signals indicative of analyte interaction, allowing for improved accuracy and speed by combining responses from multiple sites to determine analyte properties.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Measurement precision
If a sensor is designed for high sensitivity to detect low analyte concentrations, then the measurement precision is improved, but the dynamic range is reduced
Solution Approach 1:
The sensor assembly is divided into multiple sensing sites (first sensing site, second sensing site, etc.), each with distinct through hole configurations. Each sensing site operates optimally within a specific concentration range, allowing the system to segment the overall detection task across multiple specialized sites rather than requiring a single site to handle all concentrations effectively.
Solution Approach 2:
Each sensing site is given a unique local quality through its specific through hole configuration (different dimensions, shapes, or arrangements). This local differentiation enables each site to have optimized sensitivity characteristics for particular analyte concentration ranges, with the control unit selecting the most appropriate sensing site based on the expected analyte concentration.
2Measurement precision
If a sensor requires equilibrium to be established for accurate measurement, then the measurement precision is improved, but the measurement time is increased
Solution Approach 1:
The system performs preliminary action by using a first sensing site to obtain an initial indication of analyte concentration quickly, before equilibrium is fully established. Based on this preliminary measurement, the control unit determines whether to proceed with a more accurate measurement using a second sensing site with a different through hole configuration that is better suited for the detected concentration range.
Solution Approach 2:
The sensor assembly dynamically adapts its measurement strategy based on real-time conditions. The control unit adjusts which sensing site is used for final measurement based on the initial indication, allowing the system to optimize between speed and accuracy depending on the analyte concentration detected, rather than requiring equilibrium for all measurements.
3Adaptability or versatility
If multiple sensing sites with different through hole configurations are used, then the dynamic range is improved, but the device complexity is increased
Solution Approach 1:
Multiple sensing sites with different through hole configurations are integrated into a single sensor assembly, making the device universal capable of detecting analytes across a broad dynamic range. The control unit selects the appropriate sensing site based on the expected analyte concentration, allowing one device to perform multiple detection functions that would otherwise require separate sensors.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The sensor assembly enhances accuracy and speed of analyte detection by utilizing multiple sensing sites with different through hole configurations, enabling wider dynamic sensing ranges without sacrificing precision and reducing measurement time.
Implementation Method 1
a capture species configured to specifically bind with a target analyte provided to the sensing layer
Data Source
AI summary
The present disclosure provides a sensor assembly for a target analyte. The sensor assembly comprises plural sensing sites, each of the sensing sites comprising one or more through holes. Each of the sensing sites has a different through hole configuration corresponding to a different property of the one or more through holes.