Synergistic Antimicrobial Formulation Using Thyme Oil and Lauric Arginate

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Solution Overview

Problem

Current antimicrobial solutions for food products face challenges due to high concentrations of essential oils required for effectiveness, which result in undesirable flavor and odor, and the use of synthetic emulsifiers like polysorbate 80, leading to negative consumer perceptions and limited acceptance.

Innovation Solution

A synergistic combination of thyme essential oil and lauric arginate in a stable emulsion, without polysorbate 80, at a 3.5:1 ratio, which reduces the concentration of essential oils needed for antimicrobial efficacy below sensory thresholds, providing a 'clean-label' solution that maintains antimicrobial potency.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If high concentrations of essential oils are used to achieve antimicrobial effectiveness, then antimicrobial potency is improved, but flavor and odor become undesirable

Engineering Contradiction:
Improveantimicrobial effectivenessVSAvoidflavor and odor impact
Core Design Contradiction:
ReliabilityVSObject-generated harmful factors

Solution Approach 1:

The patent combines lauric arginate with essential oil or plant extract to create a synergistic antimicrobial formulation. This merging of two antimicrobial agents allows each component to enhance the other's effectiveness, enabling the use of lower essential oil concentrations while maintaining or improving antimicrobial potency, thus reducing unwanted flavor and odor impact.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The invention creates a composite antimicrobial system by formulating lauric arginate with essential oil or plant extract. This composite formulation leverages the complementary mechanisms of action between the cationic surfactant (lauric arginate) and the phenolic compounds in essential oils, achieving enhanced antimicrobial activity at reduced essential oil concentrations that remain below sensory thresholds.

Inventive Principle:
Principle #40Composite materials

2Stability of the object's composition

If synthetic emulsifiers like polysorbate 80 are used to create stable emulsions, then emulsion stability is improved, but consumer acceptance decreases due to negative perceptions

Engineering Contradiction:
Improveemulsion stabilityVSAvoidconsumer acceptance
Core Design Contradiction:
Stability of the object's compositionVSAdaptability or versatility

Solution Approach 1:

The patent removes synthetic emulsifiers like polysorbate 80 from the formulation, extracting only the essential functional components (lauric arginate and essential oil/plant extract). This elimination of synthetic additives maintains emulsion stability through the inherent properties of lauric arginate while improving consumer acceptance by providing a clean-label product without controversial synthetic emulsifiers.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

Lauric arginate serves dual functions in the formulation: it acts as both the antimicrobial agent and the emulsifying component. This self-service capability of lauric arginate to provide both antimicrobial activity and emulsion stability eliminates the need for separate synthetic emulsifiers, maintaining product stability while aligning with clean-label consumer preferences.

Inventive Principle:
Principle #25Self-service

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The combination effectively suppresses spoilage microorganisms at lower concentrations, reducing flavor impact and allowing for 'clean-label' designation, enhancing consumer acceptance and product stability without the need for synthetic emulsifiers.

Implementation Method 1

Surprising synergies were observed between thyme essential oil and lauric arginate in a markedly reduced concentration compared to previous formulations

Methodology Applied
Scientific EffectSynergistic interaction:

Implementation Method 2

The present invention relates to antimicrobial compositions comprising a plant essential oil extract and lauric arginate, wherein the composition is in the form of a stabile emulsion

Methodology Applied
Scientific EffectEmulsion: Emulsion

Data Source

PatentUS12016340B2Synergistic antimicrobial formulation consisting of plant extract and lauric arginate
Publication Date: 2024.06.25 KALAMAZOO HLDG INC
  • US12016340B2 patent drawing
  • US12016340B2 patent drawing
  • US12016340B2 patent drawing

AI summary

The present invention relates to novel synergistic compositions comprising known “clean-label” antimicrobial substances as well as processes for stabilizing food substances against typical food borne spoilage microorganisms and/or pathogens. It is a further object of the invention to provide novel combinations of “clean-label” antimicrobials which may be employed in such a process.