Thyroid Nodule Ablation with Impedance-Driven Audio Feedback

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Solution Overview

Problem

Conventional thyroid nodule ablation techniques using the 'moving shot' method face challenges such as undesirable patient responses to audible 'tissue popping' during procedures, inefficient energy delivery, and potential undertreatment or overtreatment of tissues due to fixed electrode techniques, which can lead to longer procedure times and reduced ablation efficiency.

Innovation Solution

An ablation system that includes an electrosurgical generator with an integrated audio device providing feedback correlated to tissue impedance, allowing clinicians to adjust the pace of electrode retraction based on audible and tactile cues, ensuring efficient energy delivery and minimizing 'tissue popping' during the 'moving shot' technique.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If the moving-shot technique is used with high energy levels to produce vigorous ablation, then ablation efficiency is improved, but tissue popping occurs causing undesirable patient responses

Engineering Contradiction:
Improveablation efficiencyVSAvoidtissue popping
Core Design Contradiction:
ProductivityVSObject-affected harmful factors

Solution Approach 1:

The system employs real-time impedance monitoring that provides continuous feedback to the operator. As tissue impedance changes during ablation (indicating tissue state changes), the system alerts the operator to adjust energy delivery or electrode movement, preventing excessive energy that causes tissue popping while maintaining efficient ablation through optimized parameter adjustment.

Inventive Principle:
Principle #23Feedback

2Reliability

If the electrode is held in place for a longer period to achieve desired ablation zone, then ablation completeness is improved, but procedure time increases

Engineering Contradiction:
Improveablation completenessVSAvoidprocedure time
Core Design Contradiction:
ReliabilityVSLoss of time

Solution Approach 1:

The system replaces mechanical timing and operator judgment with automated electrical impedance monitoring. Impedance changes provide real-time information about tissue ablation status, allowing the system to determine when adequate ablation has been achieved without requiring prolonged electrode residence time, thereby reducing procedure time while ensuring completeness.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

3Speed

If higher energy levels are delivered to produce vigorous ablation, then ablation speed is improved, but energy delivery efficiency decreases due to tissue impedance changes

Engineering Contradiction:
Improveablation speedVSAvoidenergy delivery efficiency
Core Design Contradiction:
SpeedVSLoss of energy

Solution Approach 1:

The system dynamically monitors tissue impedance and uses this information to adjust energy delivery parameters in real-time. When impedance changes indicate altered tissue conditions (such as drying or charring), the system modifies energy levels to maintain optimal ablation efficiency, preventing energy loss while preserving ablation speed through adaptive parameter optimization.

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The system enables shorter procedure times with improved ablation volume reduction by providing real-time auditory feedback on tissue impedance, allowing for precise control of electrode movement and energy delivery, thus enhancing the efficiency and effectiveness of thyroid nodule ablation.

Implementation Method 1

delivering energy to the thyroid nodule... delivering energy to the target tissue to achieve a desired tissue temperature

Methodology Applied
Scientific EffectJoule heating: Joule Heating

Implementation Method 2

ablating target tissue... ablation of the target tissue can be observed such that the nodule is visible and the electrode can be observed percutaneously entering the surgical site and ablating the target tissue

Methodology Applied
Scientific EffectAblation: Ablation

Implementation Method 3

sense impedance of tissue being ablated by the ablation device

Methodology Applied
Scientific EffectElectrical impedance sensing: Electrical Resistance

Data Source

PatentUS20240268879A1Systems and methods for ablation of a thyroid nodule
Publication Date: 2024.08.15 MEDTRONIC XOMED LLC
  • US20240268879A1 patent drawing
  • US20240268879A1 patent drawing
  • US20240268879A1 patent drawing

AI summary

A system for ablating a thyroid nodule using a moving shot technique includes an ablation device configured to be inserted into a thyroid nodule. The ablation device has an electrode configured to be retracted along an axis defined through the thyroid nodule while delivering energy to the thyroid nodule. The system also includes an electrosurgical generator configured to delivery energy to the ablation device. An audio device is in communication with the electrosurgical generator. The audio device is configured to broadcast a sound correlated with at least one sensed tissue property such that the audio device changes the sound in response to a change in the at least one sensed tissue property.