Transient-State THz Spectrometer Evanescent Wave Coupling

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Solution Overview

Problem

Traditional terahertz time domain spectroscopy systems in free space are limited in their ability to perform fine measurements on smaller-sized, water-containing biological samples and are affected by water absorption, making them unsuitable for transient-state dynamics research.

Innovation Solution

A transient-state THz spectrometer that couples terahertz waves into evanescent waves or pseudo surface plasmons using a horn-like gradient structure in an oxygen-free copper metal slab waveguide, enhancing local field strength and coupling efficiency for detection of trace cells and biological macromolecules.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If traditional free-space THz-TDS system is used, then the system structure is simple, but the measurement precision is insufficient for small-sized and water-containing biological samples due to diffraction limit and water absorption

Engineering Contradiction:
Improvedetection precision of biological samplesVSAvoidsystem structure complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent introduces a metal slab waveguide as an intermediary component between the THz source and the sample. The waveguide confines and guides the THz waves, enabling evanescent wave interaction with the sample. This intermediary structure overcomes the diffraction limit of free-space propagation and enhances the interaction strength, thereby improving measurement precision for small-sized and water-containing biological samples.

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The patent changes the propagation mode parameter of THz waves from free-space propagation to waveguide-confined evanescent wave propagation. This parameter change transforms the electromagnetic field distribution, creating a highly confined evanescent field that exponentially decays from the waveguide surface, thereby enhancing the interaction with near-surface biological samples and improving detection precision.

Inventive Principle:
Principle #35Parameter changes

2Productivity

If free-space THz propagation is used, then the coupling is simple, but the detection time is long and single measurement capability is not achieved

Engineering Contradiction:
Improvedetection speed and single measurement capabilityVSAvoidwaveguide structure complexity
Core Design Contradiction:
ProductivityVSDevice complexity

Solution Approach 1:

The metal slab waveguide acts as a mediator that enables single-shot detection. By confining the THz waves in the waveguide, the evanescent field interacts strongly with the sample during the brief pulse duration, allowing transient-state dynamics to be captured in a single measurement rather than requiring multiple scans as in free-space systems.

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The system uses periodic femtosecond laser pulses to generate THz pulses through photoconductive antenna excitation. Each laser pulse generates a THz pulse that interacts with the sample, and by synchronizing the detection with this periodic action, the system achieves single measurement capability for transient-state dynamics while maintaining high detection speed.

Inventive Principle:
Principle #19Periodic action

3Measurement precision

If evanescent wave coupling is implemented, then the local field enhancement is achieved, but the device complexity increases due to waveguide and coupling structures

Engineering Contradiction:
Improvelocal field enhancement for trace detectionVSAvoidwaveguide and coupling structure complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent changes the electromagnetic field confinement parameter by transitioning from free-space propagation to waveguide-confined evanescent wave propagation. This parameter change creates exponential field decay away from the waveguide surface, concentrating the field energy in a small region near the sample, thereby achieving local field enhancement that improves detection sensitivity for trace cells and biological macromolecules.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The evanescent wave field exhibits local quality by being highly concentrated near the waveguide surface and exponentially decaying with distance. This local field enhancement allows the system to achieve high measurement precision for trace samples in a localized region, compensating for the increased device complexity through targeted field concentration rather than uniform field distribution.

Inventive Principle:
Principle #3Local quality

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Enables single measurement and high-accuracy detection of water-containing biological samples at a femtomolar level with reduced water absorption influence, achieving short detection times and improved measurement precision.

Implementation Method 1

the pump light is focused to irradiate a gap between electrodes of a nonlinear photoconductive antenna and emit a terahertz wave

Methodology Applied
Scientific EffectOptical rectification:

Implementation Method 2

the terahertz wave collineation and the probe light form a probe light collineation of wavefront tilt which is perpendicularly incident on a ZnTe crystal

Methodology Applied
Scientific EffectElectro-optic effect:

Implementation Method 3

The probe light obtained by the beam splitter successively passes through a blazed grating and a silver-plated reflector and is reflected to a first polarizer

Methodology Applied
Scientific EffectDiffraction: Diffraction

Implementation Method 4

the pump light is focused to irradiate a gap between electrodes of a nonlinear photoconductive antenna

Methodology Applied
Scientific EffectFocusing: Focusing

Data Source

PatentUS11692935B2Transient-state THz spectrometer for detecting cells and biological macromolecules
Publication Date: 2023.07.04 XIAN UNIV OF TECH
  • US11692935B2 patent drawing
  • US11692935B2 patent drawing

AI summary

Disclosed is a transient-state THz spectrometer applied to cells and biological macromolecules, including a femtosecond laser amplifier. A femtosecond laser output by the femtosecond laser amplifier is divided into two beams of pump light and probe light after passing through a beam splitter of which a transmission-reflection ratio is 7:3, the pump light is focused to irradiate a gap between electrodes of a nonlinear photoconductive antenna and emit a terahertz wave after successively passing through a half wave plate, a silver-plated reflector and a first lens, the terahertz wave forms a terahertz wave collineation after successively passing through a second lens, a slab waveguide, a third lens and an ITO film, the terahertz wave collineation and the probe light form a probe light collineation of wavefront tilt which is perpendicularly incident on a ZnTe crystal and detected and recorded by using a CCD camera.