Time-Controlled Pill with Dissolving Filler for Drug Interaction Prevention

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Solution Overview

Problem

Conventional approaches to medication delivery do not effectively manage time gaps between multiple medications, leading to potential drug interactions and adverse side effects.

Innovation Solution

A method that determines a dissolving pattern specific to a patient, incorporating a medication dissolving rate and a filler dissolving rate to create a time gap between medications, ensuring they are taken at appropriate intervals to prevent interactions.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of operation

If medications are taken according to conventional frequency instructions without time gap control, then patient compliance is simplified, but drug interactions and adverse side effects occur

Engineering Contradiction:
Improvepatient complianceVSAvoiddrug interactions
Core Design Contradiction:
Ease of operationVSObject-affected harmful factors

Solution Approach 1:

The pill is segmented into multiple functional layers: an outer medication layer that dissolves first, an inner medication layer that dissolves later, and a time-gap filler layer in between. This segmentation ensures that the first medication is released before the second medication, creating a controlled time gap that prevents drug interactions while maintaining simple patient compliance.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The time-gap filler acts as an intermediary substance between the first and second medications. This filler material occupies space and time in the digestive tract, ensuring that the first medication dissolves and is metabolized before the second medication is released, thereby preventing harmful drug interactions.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Object-affected harmful factors

If a time gap is created between medications using conventional methods, then drug interactions are prevented, but pill complexity increases

Engineering Contradiction:
Improveadverse side effectsVSAvoidpill structure
Core Design Contradiction:
Object-affected harmful factorsVSDevice complexity

Solution Approach 1:

The pill employs a nested structure where the inner medication layer is enclosed within the outer medication layer, with the time-gap filler layer positioned between them. This nested arrangement allows multiple medications to be contained in a single pill while maintaining distinct dissolution timing, preventing adverse side effects without excessive complexity.

Inventive Principle:
Principle #7Nested doll (Nesting)

Solution Approach 2:

The patent utilizes parameter changes in dissolution rates by selecting specific materials for the outer medication layer, inner medication layer, and time-gap filler layer. Each layer is designed with different dissolution characteristics, allowing the outer layer to dissolve faster than the inner layer, thereby creating a controlled time gap that prevents drug interactions.

Inventive Principle:
Principle #35Parameter changes

3Measurement precision

If personalized dissolving patterns are determined for each patient, then medication timing precision is improved, but manufacturing complexity increases

Engineering Contradiction:
Improvedissolving pattern determinationVSAvoidmanufacturing process
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent performs preliminary determination of the patient's dissolving pattern through trial tests before finalizing the pill formulation. This preliminary action allows the system to calculate the specific dissolution rates for the outer medication layer, inner medication layer, and time-gap filler layer based on the patient's individual characteristics, improving timing precision while managing manufacturing complexity through standardized formulation processes.

Inventive Principle:
Principle #10Preliminary action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The solution effectively prevents drug interactions by ensuring a sufficient time gap between medication releases, thereby reducing the risk of adverse effects and improving treatment efficacy.

Implementation Method 1

determining a dissolving pattern for the patient. The dissolving pattern includes a medication dissolving rate for a first medication prescribed to the patient and a filler dissolving rate for a filler selected so that the time gap is elapsed prior to a second medication being provided

Methodology Applied
Scientific EffectDissolution:

Data Source

PatentUS12251208B2Time controlled medication
Publication Date: 2025.03.18 INTERNATIONAL BUSINESS MACHINE CORPORATION
  • US12251208B2 patent drawing
  • US12251208B2 patent drawing
  • US12251208B2 patent drawing

AI summary

A method, a computer program product, and a computer system provide medications to a patient with a time gap. The method includes determining a dissolving pattern for the patient. The dissolving pattern includes a medication dissolving rate for a first medication prescribed to the patient and a filler dissolving rate for a filler selected so that the time gap is elapsed prior to a second medication being provided after the first medication. The medication dissolving rate and the filler dissolving rate are specific to the patient. The method includes determining dimensions of the first medication to correspond to a dosage of the prescribed first medication and dimensions of the filler to correspond to the time gap. The method includes providing a pill including at least the first medication and the filler, the first medication surrounding the filler such that the first medication is dissolved prior to the filler being dissolved.