Time Gate Optical Path Reference Concentration Measurement Apparatus
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Solution Overview
Problem
Current non-invasive near-infrared spectroscopy methods for blood glucose detection face challenges in accurately extracting weak glucose concentration information due to background changes, which complicates real-time monitoring and quantitative measurement.
Innovation Solution
A method that uses a light intensity reference value measured at a benchmark position with minimal sensitivity to glucose concentration changes to correct light intensity measurement values, effectively isolating the glucose concentration signal from background interference by employing a time gate fixed optical length technique.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Measurement precision
If conventional spectral data processing methods are used, then the measurement can be performed, but the accuracy is limited due to background changes affecting the detection of weak glucose concentration signals
Solution Approach 1:
The patent segments the spectral data processing into multiple components: reference spectrum acquisition, measurement spectrum acquisition, and differential correction calculation. By dividing the measurement process into distinct stages and applying separate correction factors for different spectral regions, the method effectively isolates and eliminates background interference while preserving glucose concentration information
Solution Approach 2:
The patent introduces a reference spectrum as an intermediary element that captures the background characteristics without glucose concentration variations. This reference spectrum serves as a mediator between the light source and the measurement spectrum, allowing the system to subtract background effects and extract pure glucose concentration signals through differential correction
2Measurement precision
If multiple spectral processing methods are combined, then measurement accuracy can be improved, but the device complexity and processing difficulty increase
Solution Approach 1:
The patent transforms the spectral data processing by changing parameters such as optical path length and spectral wavelength selection. By adjusting these parameters to identify regions where background changes are minimal while glucose absorption varies significantly, the method achieves high measurement accuracy through relatively simple differential correction calculations rather than complex multi-method processing
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
This approach enhances measurement accuracy by reducing the impact of background changes, allowing for more precise and reliable detection of blood glucose levels, improving the signal-to-noise ratio and facilitating real-time monitoring.
Implementation Method 1
an optical detector configured to detect photons transmitted through the measured object
Implementation Method 2
a time gate device configured to separate photons transmitted through the measured object into a plurality of time gates according to transmission time of the photons
Implementation Method 3
near-infrared spectroscopy technology has been widely applied to detect concentrations of substance components
Data Source
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AI summary
The present disclosure provides a method for correcting a light intensity measurement value is provided, characterized in that, the method includes: emitting detection light into a measured object; measuring a light intensity measurement value at a measurement position, and measuring light intensity of photons at a benchmark position as a light intensity reference value, wherein a sensitivity of the light intensity of photons to a concentration change of a specific substance in the measured object is less than or equal to a preset threshold, and a change rate of the light intensity at the measurement position with a concentration of the specific substance in the measured object is greater than a change rate of the light intensity at the benchmark position with the concentration of the specific substance; correcting the light intensity measurement value by using the light intensity reference value. The present disclosure further provides a concentration measurement device in which the above method is applied.