Real-Time Tissue Activation Visualization for Neurostimulation
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Solution Overview
Problem
Current neurostimulation systems face challenges in efficiently programming optimal stimulation parameter sets due to the complexity of electrode configurations and the need for precise tissue targeting, often requiring lengthy clinical sessions and potential side effects from non-selective tissue stimulation.
Innovation Solution
A system featuring a user-controlled input device and processor that generates and adjusts stimulation parameter sets, allowing for directional control of electrical current between electrodes, and provides animated graphical representations of tissue activation, facilitating more efficient and precise targeting of stimulation regions.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Ease of operation
If traditional neurostimulation programming methods are used, then clinicians can adjust stimulation parameters, but the programming process becomes time-consuming and complex due to multiple electrode configurations
Solution Approach 1:
The patent creates a visual copy or representation of the tissue activation region through graphical display, allowing clinicians to see the effect of parameter changes before actual implementation. This visual modeling enables faster parameter optimization without extensive trial-and-error programming sessions
Solution Approach 2:
The system automatically adjusts stimulation parameters based on visual feedback from the graphical representation of tissue activation. By linking parameter changes to visual outcomes, the system reduces the manual programming complexity and time required to achieve optimal stimulation
2Reliability
If electrical stimulation is applied to target tissue, then therapeutic effects are achieved, but non-selective stimulation of neighboring tissues causes side effects
Solution Approach 1:
The patent enables precise control over the spatial distribution of electrical stimulation by allowing selective activation of specific electrode combinations. The graphical representation shows the localized region of tissue activation, enabling clinicians to confine stimulation to the intended target area while avoiding adjacent sensitive tissues through localized current steering
Solution Approach 2:
The electrode array is divided into multiple independently controllable segments or combinations. By selecting specific electrode pairs or groups, the system can segment the stimulation field to target only the desired tissue region, preventing spread to neighboring areas and reducing unwanted side effects
3Adaptability or versatility
If multiple electrode combinations are available for stimulation, then flexible current distribution is achieved, but the complexity of selecting optimal parameters increases
Solution Approach 1:
The system provides visual feedback through graphical display showing the region of tissue activation for different electrode combinations and parameter settings. This feedback loop allows clinicians to see the immediate effect of parameter changes on the visualized tissue, simplifying the selection process by making the consequences of each configuration visible and understandable
Solution Approach 2:
The graphical representation acts as an intermediary between the complex electrode configurations and the clinician's decision-making process. Rather than directly interpreting multiple electrical parameters, the clinician interacts with the visual model that translates parameter combinations into understandable spatial patterns of tissue activation
Data Source
AI summary
A system for a tissue stimulator coupled to an array of electrodes. The system comprises a user-controlled input device configured for generating control signals, and at least one processor configured for generating a plurality of stimulation parameter sets in response to the control signals that, when applied to the electrodes, will shift electrical current between electrodes to modify a region of tissue activation. The processor(s) is further configured for computing an estimate of the region of tissue activation, and for generating display signals capable of prompting a monitor to display an animated graphical representation of the computed estimate of the region of tissue activation.