Repositionable Tissue Capture Sleeve for Complete Endoscopic Resection
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Solution Overview
Problem
Existing tissue removal procedures, such as full thickness resection, pose risks like intrabdominal hypertension and cancer cell seeding, while partial resections often fail to remove the entirety of target tissue.
Innovation Solution
A tissue capture device with a removably attachable sleeve and control loops, allowing precise capture and removal of target tissue through a flexible endoscope, minimizing contact with healthy tissue and reducing the risk of seeding.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Manufacturing precision
If full thickness resection is performed to completely remove target tissue, then the completeness of tissue removal is improved, but the risk of intrabdominal hypertension and cancer cell seeding increases
Solution Approach 1:
The device segments the tissue removal process into distinct phases: capture, containment, and removal. The capture sleeve divides the resection cavity into isolated compartments, preventing cancer cells from dispersing while maintaining complete tissue removal. This segmentation allows the surgeon to achieve thorough resection without the harmful side effects of traditional full-thickness resection.
Solution Approach 2:
The capture sleeve acts as an intermediary barrier between the resection site and the abdominal cavity. It contains the resected tissue and any potential cancer cells within the sleeve during removal, preventing direct contact with surrounding tissues and eliminating the seeding risk while allowing complete tissue extraction.
2Object-affected harmful factors
If partial resection is performed to reduce procedural risk, then the risk of intrabdominal hypertension is reduced, but the completeness of target tissue removal is compromised
Solution Approach 1:
The device allows partial resection to proceed with reduced risk while the capture sleeve segments and contains any remaining tissue fragments. This ensures that even if the resection is not completely thorough, all residual tissue is captured and removed, achieving both risk reduction and completeness.
3Stability of the object's composition
If a fixed tissue capture device is used, then the structural stability is improved, but the ability to adapt to different tissue locations and sizes is reduced
Solution Approach 1:
The capture sleeve transitions from a collapsed low-profile state during insertion to an expanded stable state during tissue capture. This dynamic transformation allows the device to adapt to various tissue locations and sizes while maintaining structural stability when deployed. The sleeve can be adjusted to accommodate different resection cavity dimensions.
Solution Approach 2:
The capture sleeve is constructed from flexible materials that allow it to conform to different anatomical structures and tissue configurations. This flexibility enables adaptation to various tissue locations and sizes while the sleeve maintains its structural integrity once deployed, providing both adaptability and stability.
4Manufacturing precision
If a complex tissue capture mechanism is used to ensure complete tissue removal, then the completeness of tissue removal is improved, but the device complexity increases
Solution Approach 1:
The device extracts the tissue capture function from complex mechanical mechanisms and implements it through a simple yet effective capture sleeve structure. This sleeve can be deployed through minimal actuation, reducing device complexity while maintaining the ability to achieve complete tissue removal through its containment and retrieval capabilities.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The device enables safe and complete removal of target tissue with minimized risk of cancer cell dissemination and reduced procedural complications.
Implementation Method 1
The first tube is configured to push the tissue capture sleeve distally off of the insertion device when the first tube is advanced distally through the first hollow member
Implementation Method 2
the elastomeric loop being biased toward a closed configuration so that, when the tissue capture sleeve is pushed distally off of the insertion device, the elastomeric loop pulls the proximal opening of the tissue capture sleeve closed
Data Source
AI summary
A device includes a capture assembly, a hollow member, a tube, and a control member. The assembly includes a capture sleeve received on a distal end of an insertion device and a flange mounted on the insertion device proximal of the sleeve. The hollow member, the tube, and the control member each have a proximal end accessible by the user. The tube pushes the sleeve distally off the insertion device when the tube is advanced distally through the hollow member. The control member includes a distal end forming a loop coupled around a circumference of a distal opening of the sleeve. The loop moves between a constricted configuration in which at least a portion of the loop is drawn proximally into the tube and an open configuration in which the loop is extended distally from the tube to open the loop and the distal opening of the sleeve.