Tissue Cassette With Adhesive Positioning and Permeable Shell

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Solution Overview

Problem

Current tissue transport containers face challenges in securely positioning and preserving tissue samples during transport, particularly in low-germ environments, which can lead to sample damage, mixing, and inefficient processing, and lack a means for easy identification and labeling.

Innovation Solution

A tissue cassette with an outer shell and base featuring an adhesive layer for secure sample positioning, a detachable liquid-permeable inner shell, and markings for sample orientation and identification, allowing for efficient paraffin treatment and resource-saving processing.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If a tissue sample is placed in a transport container without a positioning means, then the container is simpler in structure, but the tissue sample cannot be securely positioned and may shift or break during transport

Engineering Contradiction:
Improvesecure positioning of tissue sampleVSAvoidstructure of transport container
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The positioning means is segmented into multiple independent elements (protrusions and recesses) that can be distributed across the base and lid of the container. This allows the tissue sample to be secured at multiple points without requiring a complex overall structure, resolving the contradiction between reliability and device complexity.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The positioning means acts as an intermediary mechanism between the tissue sample and the transport container walls. Rather than requiring direct contact between the sample and container walls (which would increase complexity), the positioning elements mediate this interaction, providing secure positioning through a simple, modular structure.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Reliability

If the transport container has a complex positioning system, then the tissue sample can be securely positioned, but the preparation and labeling process becomes more time-consuming

Engineering Contradiction:
Improvesecure positioning of tissue sampleVSAvoidtime for preparation and labeling
Core Design Contradiction:
ReliabilityVSLoss of time

Solution Approach 1:

The positioning means is pre-configured in the container structure with protrusions and recesses that automatically align the tissue sample during insertion. This preliminary arrangement eliminates the need for time-consuming manual positioning and labeling operations, while maintaining reliable sample securing.

Inventive Principle:
Principle #10Preliminary action

3Ease of manufacture

If the tissue sample is allowed to move freely in the transport container, then the container is simpler to manufacture, but the tissue sample may assume a position that complicates subsequent processing

Engineering Contradiction:
Improvemanufacture of transport containerVSAvoidsubsequent processing of tissue sample
Core Design Contradiction:
Ease of manufactureVSEase of operation

Solution Approach 1:

The positioning means provides localized securing features (protrusions and recesses) at specific locations within the container, rather than requiring a complex overall structure. This allows the container to remain simple to manufacture while ensuring the tissue sample is positioned in an optimal location for subsequent processing operations.

Inventive Principle:
Principle #3Local quality

4Reliability

If the transport container lacks an adhesive layer, then the container structure is simpler, but the tissue sample cannot be immovably positioned on the base

Engineering Contradiction:
Improveimmovable positioning of tissue sampleVSAvoidadhesive layer on base
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The positioning means uses a repeating pattern of protrusions and recesses that can be manufactured using simple molding or stamping techniques. This copied structure provides reliable positioning without requiring complex adhesive applications, resolving the contradiction between reliability and device complexity.

Inventive Principle:
Principle #26Copying

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The cassette ensures reliable, quick, and high-quality sample positioning and processing, minimizing sample damage and mixing, while enabling efficient communication of sample information through positioning and markings, facilitating accurate analysis.

Implementation Method 1

the means for positioning on the base is an adhesive layer on the base, wherein the adhesive layer is an adhesive applied to the base of the cassette which adheres sufficiently to position an untreated tissue sample immovably

Methodology Applied
Scientific EffectAdhesion: Adhesive

Implementation Method 2

wherein the inner shell has a liquid-permeable base

Methodology Applied
Scientific EffectPermeation: Permeation

Data Source

PatentEP3150278B1Tissue cassette
Publication Date: 2019.08.07 EUROIMMUN MEDIZINISCHE LABORDIAGNOSTIKA
  • EP3150278B1 patent drawingFigure 1A~1C
  • EP3150278B1 patent drawingFigure 1D
  • EP3150278B1 patent drawingFigure 2A~2C

AI summary

The present invention relates to a fabric cassette comprising an outer shell formed of walls and a base with a means for positioning a fabric sample on the base; and to a method comprising the steps of providing the fabric cassette and inserting a fabric sample and positioning the same on the base.