Tissue Collection System with Rotating Fenestrated Member

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Solution Overview

Problem

Conventional tissue collection and processing techniques are cumbersome, time-consuming, and prone to contamination, particularly in fat transfer procedures, due to the need for multiple steps and devices, which increases the risk of tissue trauma and microbial contamination.

Innovation Solution

A tissue collection system comprising an outer housing with a first immovable cylindrical fenestrated member and a second rotatable cylindrical fenestrated member, along with a plunger and elongate rod, allows for fluid communication control between inner and outer tissue collection chambers, enabling streamlined harvesting, processing, and reinjection of tissue within a single disposable device.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If conventional washing and processing techniques are used, then tissue can be treated and refined, but the process becomes time-consuming and increases contamination risk

Engineering Contradiction:
Improvecontamination riskVSAvoidprocessing time
Core Design Contradiction:
ReliabilityVSLoss of time

Solution Approach 1:

The patent combines multiple processing functions (washing, centrifugation, filtration, and tissue collection) into a single integrated device. The collection chamber serves as both the harvesting vessel and the processing chamber, eliminating the need to transfer tissue between multiple devices and containers, thereby reducing contamination risk and processing time.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The collection chamber is designed to perform multiple functions: it collects tissue during harvesting, serves as the centrifugation chamber during processing, and acts as the injection chamber for fat transfer. This multi-functionality eliminates the need for separate devices for each step, reducing both time and contamination risk.

Inventive Principle:
Principle #6Universality (Multi-functionality)

2Adaptability or versatility

If multiple devices and steps are used for tissue harvesting and processing, then tissue can be treated, but device complexity increases and contamination risk rises

Engineering Contradiction:
Improveprocessing capabilityVSAvoidnumber of devices
Core Design Contradiction:
Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The patent integrates harvesting, processing, and injection functions into a single device with a unified collection chamber. The chamber includes integrated components such as the piston for centrifugation, filtration elements, and injection port, eliminating the need for multiple separate devices while maintaining full processing capability.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The collection chamber is designed as a universal vessel that can perform harvesting, washing, centrifugation, filtration, and injection functions. The chamber's design allows it to adapt to different processing steps without requiring device changes, thereby reducing overall system complexity.

Inventive Principle:
Principle #6Universality (Multi-functionality)

3Ease of operation

If manual handling and multiple transfers are performed, then tissue can be processed, but tissue trauma increases and contamination risk rises

Engineering Contradiction:
Improvemanual handlingVSAvoidtissue trauma
Core Design Contradiction:
Ease of operationVSObject-affected harmful factors

Solution Approach 1:

The patent combines the collection chamber with the processing chamber, eliminating the need to manually transfer tissue between devices. The piston mechanism performs centrifugation and washing within the same chamber, reducing mechanical handling and associated tissue trauma.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The system performs washing and centrifugation automatically using the piston mechanism and integrated filtration, minimizing the need for manual intervention. The tissue remains in the collection chamber throughout the process, and the system self-regulates the washing and separation functions without requiring manual transfers.

Inventive Principle:
Principle #25Self-service

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This system simplifies the fat transfer process, reduces contamination risks, and shortens training times for professionals by integrating all functions into a single device, improving safety and efficiency in tissue collection and delivery.

Implementation Method 1

The second cylindrical fenestrated member is positioned within and rotatable relative to the first cylindrical fenestrated member between an open position in which the fenestrations of the first cylindrical fenestrated member and the fenestrations of the second cylindrical fenestrated member are in registration with one another, thereby permitting fluid communication between the inner tissue collection chamber and the outer tissue collection chamber

Methodology Applied
Scientific EffectFluid communication control through rotational positioning:

Implementation Method 2

A plunger is axially movable within the second fenestrated cylindrical member between an advanced position near the distal end of the outer housing and a retracted position near the proximal end of the outer housing

Methodology Applied
Scientific EffectFluid aspiration through plunger movement: Suction

Data Source

PatentUS9480464B2Tissue collection system
Publication Date: 2016.11.01 NEW YORK UNIV
  • US9480464B2 patent drawing
  • US9480464B2 patent drawing
  • US9480464B2 patent drawing

AI summary

The present invention relates to a tissue collection system. The system includes an outer housing, a first cylindrical fenestrated member within and immovable relative to the outer housing, a second cylindrical fenestrated member defining an inner tissue collection chamber and being positioned within and rotatable relative to the first cylindrical fenestrated member, a plunger axially movable within the second fenestrated member, an elongate rod being connected to the plunger, and one or more stop units attached to the outer housing. The present invention also relates to methods for separating components of a tissue sample using a system according to the present invention.