Tissue Dividing Jig for Biopsy Fragment Alignment

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Solution Overview

Problem

Existing biopsy techniques face challenges in accurately dividing needle biopsy tissues into multiple fragments without deformation or misalignment, making it difficult to perform consistent analysis, especially for prostate cancer where tissue properties vary irregularly.

Innovation Solution

A tissue dividing jig with a tissue placement portion, cutting blade set, and positioning mechanism that guides the cutting blade to divide the tissue in a longitudinal direction, allowing for precise division into two or more fragments with spatial correspondence, using a sheet-like member for fixation and a biopsy needle guide for accurate placement.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of operation

If tissue is divided inside a biopsy needle, then tissue sampling is achieved, but tissue may slip or fragments may be deformed and compressed resulting in misalignment

Engineering Contradiction:
Improvetissue division operationVSAvoidtissue fragment alignment
Core Design Contradiction:
Ease of operationVSManufacturing precision

Solution Approach 1:

A sheet-like member is introduced as an intermediary between the tissue and the cutting blade. The tissue is placed on this sheet-like member which prevents slippage during cutting and maintains fragment alignment. The sheet-like member acts as a mediator that facilitates the cutting operation while preserving tissue integrity and spatial correspondence.

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The invention replaces the complex mechanical system of dividing tissue within the needle with a simpler system using a sheet-like member and cutting blade on the tissue dividing base. This substitution allows for easier operation while maintaining precision through the sheet-like member's ability to hold tissue fragments in place.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

2Manufacturing precision

If tissue is divided after being collected from the needle, then tissue deformation is avoided, but expert skill and equipment are required that are not generally available in clinics

Engineering Contradiction:
Improvetissue fragment integrityVSAvoiddivision equipment
Core Design Contradiction:
Manufacturing precisionVSDevice complexity

Solution Approach 1:

The tissue dividing base is designed to be self-contained and easy to use, requiring no expert skill or complex equipment. The device includes a tissue placement portion, cutting blade set with guide portion, and positioning mechanism that work together to enable any clinician to perform tissue division without specialized training or additional equipment.

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The invention extracts the tissue division function from complex laboratory equipment and creates a simple, standalone device that can be used directly in the clinic. By taking out the essential elements (tissue placement portion, cutting blade, guide portion) and removing unnecessary complexity, the device becomes accessible to general clinical use.

Inventive Principle:
Principle #2Taking out (Extraction)

3Manufacturing precision

If tissue is divided evenly with extreme care, then consistent division is achieved, but it remains difficult to perform consistent division over the entire length of the core

Engineering Contradiction:
Improvedivision consistencyVSAvoiddivision operation
Core Design Contradiction:
Manufacturing precisionVSEase of operation

Solution Approach 1:

The guide portion and positioning mechanism are configured in advance to establish fixed positions for the cutting blade relative to the tissue placement portion. This preliminary setup ensures that the cutting blade automatically follows a predetermined path that maintains consistent spacing and orientation throughout the entire length of the tissue core, eliminating the need for manual adjustment during the cutting process.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The invention replaces manual, skill-dependent cutting operations with a mechanically guided system. The guide portion constrains the cutting blade's movement to a fixed trajectory, substituting human skill with mechanical precision to achieve consistent division across the entire tissue length.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

4Manufacturing precision

If a positioning mechanism is provided between the tissue dividing base and cutting blade set, then consistent division is achieved, but device complexity increases

Engineering Contradiction:
Improvecutting position accuracyVSAvoidjig structure
Core Design Contradiction:
Manufacturing precisionVSDevice complexity

Solution Approach 1:

The positioning mechanism is segmented into separate, simple components: the tissue placement portion on the base, the guide portion on the cutting blade set, and the positioning features. Each component has a single, clear function, and they work together through simple geometric relationships rather than complex mechanisms. This segmentation maintains precision while minimizing overall device complexity.

Inventive Principle:
Principle #1Segmentation

Data Source

PatentUS11733130B2Tissue dividing jig
Publication Date: 2023.08.22 UMIHIRA CO LTD
  • US11733130B2 patent drawing
  • US11733130B2 patent drawing
  • US11733130B2 patent drawing

AI summary

A tissue dividing jig includes a tissue dividing base; and a cutting blade set provided with a cutting blade member and a guide portion, the tissue dividing base and the cutting blade set have a positioning mechanism that fixes their positions mutually, the cutting blade member is provided with a cutting blade extending in a longitudinal direction of the tissue placement portion, the guide portion guides the cutting blade member to move the cutting blade member to a fixed position on the tissue dividing base, and the cutting blade is disposed such that when the cutting blade set is disposed at a predetermined position on the tissue dividing base by the positioning mechanism and the cutting blade member is moved using the guide portion, the cutting blade divides the needle biopsy tissue on the tissue placement portion in the longitudinal direction.