Tissue Extraction Vessel With Suspension Support for Microbial Testing

Resolve Bottlenecks,
Find Innovative SolutionsGenerate Solutions

Solution Overview

Problem

Existing systems and methods for detecting microbial contamination of tissue products, such as allografts, xenografts, and autografts, are inefficient and inaccurate, often leading to the risk of infection due to the inability to handle large or oddly shaped tissues, damage soft tissues, and rely on methods like cotton swabs or destructive testing.

Innovation Solution

A biocompatible extraction system comprising a biocompatible outer vessel and a suspension system or inner vessel, capable of holding and agitating tissue samples in an extraction fluid to detect microbial contamination, while minimizing tissue damage and fluid volume.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Adaptability or versatility

If conventional vessels are used for microbial contamination detection, then the testing process is simple, but the system cannot hold large or oddly shaped tissue products efficiently

Engineering Contradiction:

Improveability to hold various tissue product sizes and shapesVSAvoidvessel structure complexity

Core Design Contradiction:

Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The extraction system is divided into multiple components: an outer vessel, an inner vessel, and a suspension system with horizontal and vertical members. This segmentation allows each component to be optimized for its specific function while collectively providing adaptability to various tissue product sizes and shapes.

Inventive Principle:

Principle #1Segmentation

Solution Approach 2:

The suspension system with its horizontal and vertical members can accommodate different tissue product configurations (large, small, oddly shaped, soft tissues) within a single vessel design, making the system universal for various tissue types without requiring multiple specialized vessels.

Inventive Principle:

Principle #6Universality (Multi-functionality)

2Measurement precision

If conventional testing methods (cotton swabs or destructive testing) are used, then the testing process is simple, but the detection accuracy is poor

Engineering Contradiction:

Improvemicrobial contamination detection accuracyVSAvoidtesting system complexity

Core Design Contradiction:

Measurement precisionVSDevice complexity

Solution Approach 1:

The system extracts microorganisms from the tissue product by submerging it in extraction fluid within the sealed vessel, then analyzes the fluid for microbial contamination. This extraction method provides more accurate detection compared to surface swabbing by recovering microbes from the entire tissue surface including crevices and folds.

Inventive Principle:

Principle #2Taking out (Extraction)

Solution Approach 2:

The extraction fluid acts as an intermediary medium that transfers microorganisms from the tissue product to a testable state. The fluid facilitates complete contact with the tissue surface and enables sensitive detection of microbial contamination without direct manipulation of the tissue.

Inventive Principle:

Principle #24Intermediary (Mediator)

3Object-affected harmful factors

If soft tissue products are subjected to conventional testing methods, then the testing process is straightforward, but the soft tissues become folded or damaged

Engineering Contradiction:

Improvetissue damage during testingVSAvoidtesting efficiency

Core Design Contradiction:

Object-affected harmful factorsVSProductivity

Solution Approach 1:

The suspension system is designed to support soft tissue products in a manner that prevents folding and damage before the testing process begins. The horizontal and vertical members provide structural support that maintains tissue integrity throughout the extraction and analysis process.

Inventive Principle:

Principle #11Beforehand cushioning (Prior cushioning)

Solution Approach 2:

The inner vessel and suspension components are designed with flexibility to accommodate soft tissue products without causing mechanical damage. The system allows tissues to maintain their natural configuration while being fully submerged in extraction fluid.

Inventive Principle:

Principle #30Flexible shells and thin films

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The system effectively detects microbial contamination in a wide range of tissue types, including soft tissues, reducing the risk of infection and inaccuracies associated with previous methods, and is cost-effective.

Implementation Method 1

a biocompatible outer vessel having a side wall and a biocompatible suspension system that is positionable within an interior of the biocompatible outer vessel. The biocompatible suspension system may include a horizontal member on which a tissue sample may be supported

Methodology Applied

Scientific EffectBuoyancy: Archimedes' Principle (Buoyancy)

Data Source

PatentUS20250354906A1Extraction system for testing microbial contamination of tissue products

Publication Date: 2025.11.20 ALLOSOURCE

AI summary

An extraction system for testing microbial contamination includes a biocompatible outer vessel that has a side wall and a biocompatible suspension system that is positionable within an interior of the biocompatible outer vessel. The biocompatible suspension system includes a horizontal member on which a sample may be supported and a securement mechanism that is engagable with the side wall of the biocompatible outer vessel to maintain the suspension system at a desired position within the biocompatible outer vessel.