Tissue Extraction Vial with Integrated Blade and Cap
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Solution Overview
Problem
Current methods for collecting and transporting stem cells for therapies are inefficient, as they often fail to ensure the viability and quantity of cells required for effective treatment, and may cause discomfort to patients due to the size of the tissue sample taken.
Innovation Solution
A tissue extraction device comprising a vial with a cap and a circular blade attached, designed to collect and preserve tissue samples within a sterile, leak-proof container, using a solution that can include preservatives or enzymes to maintain cell viability, allowing for efficient transportation and storage.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Quantity of substance
If a large tissue sample is taken to ensure sufficient stem cell quantity, then the cell yield for therapy is improved, but patient discomfort and trauma increase
Solution Approach 1:
The blade is designed with a specific diameter (2-4 mm) to concentrate the tissue extraction at a localized minimal invasive point, ensuring sufficient cell yield from a small sample area rather than requiring large tissue removal
Solution Approach 2:
The invention optimizes the blade diameter parameter within 2-4 mm range to balance between extracting sufficient stem cells and minimizing patient trauma, representing a parameter optimization to resolve the contradiction
2Reliability
If conventional collection methods are used, then the procedure is simple, but cell viability and quantity are insufficient for effective therapy
Solution Approach 1:
The invention merges the blade, cap, and vial into a single integrated assembly where the blade attaches directly to the cap which seals onto the vial, combining tissue extraction and cell preservation functions in one device system
Solution Approach 2:
The device serves multiple functions: the blade extracts tissue, the cap seals and protects the sample, and the vial stores and transports the cells, making a single system perform extraction, preservation, and transport functions
3Reliability
If the tissue sample is transported without special preservation, then the transport process is simple, but cell viability is lost during transport
Solution Approach 1:
The vial is pre-filled with preservation solution before the procedure, and the blade is pre-attached to the cap, so that when tissue is extracted, the cells are immediately placed in preservation medium, eliminating the need for complex post-procedure preservation steps
Solution Approach 2:
The preservation solution acts as an intermediary medium between the extracted tissue and the therapy destination, maintaining cell viability during transport by providing a suitable physiological environment
Data Source
AI summary
Disclosed is a device useful for preserving tissue samples after extraction from human or animal patients. The device includes a circular blade for taking a tissue sample, the blade being coupled to a sealing cap which mates to one end of a container. A retrieval port is also disclosed for extracting fluids from the container. Methods are also disclosed by which tissue samples may be taken and prepared for storage, processing, culture, or other analysis.