Tissue Packaging Holder Channels for Orientation-Independent Preservation

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Solution Overview

Problem

Existing tissue storage techniques require specialized refrigeration or freezer equipment, limiting facility use and complicating transportation, and involve inconvenient pre-operative preparations, with known systems often needing a specific orientation to maintain fluid seals.

Innovation Solution

A packaging system comprising a holder and inner container with channels, an outer container, and a preservation solution, allowing room-temperature storage and facilitating easy handling and preservation of tissues in a fluid environment.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If specialized refrigeration or freezer equipment is used to store tissue grafts, then tissue preservation is improved, but facility availability and transportation complexity worsen

Engineering Contradiction:
Improvetissue preservationVSAvoidtransportation complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The invention changes the storage temperature parameter from extreme cold (freezer temperatures) to refrigerated temperatures (2°C to 10°C), allowing tissue preservation without requiring specialized freezer equipment. The packaging system maintains this temperature range during storage and transportation, eliminating the need for complex cold chain logistics while preserving tissue viability.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The packaging system is divided into separate components: an outer container with insulation, an inner container holding the tissue, and a fluid reservoir. This segmentation allows the system to maintain refrigeration temperatures without requiring a single complex frozen unit, simplifying transportation and facility requirements while preserving tissue.

Inventive Principle:
Principle #1Segmentation

2Ease of manufacture

If dried tissue is used instead of wet-preserved tissue, then storage simplicity is improved, but pre-operative preparation time and inconvenience worsen

Engineering Contradiction:
Improvestorage simplicityVSAvoidpre-operative preparation time
Core Design Contradiction:
Ease of manufactureVSLoss of time

Solution Approach 1:

The tissue is pre-preserved in a fluid solution within the packaging system before use, maintaining its viability and readiness for implantation. This preliminary preservation action eliminates the need for time-consuming rehydration or preparation procedures that would be required if dried tissue were used, allowing surgeons to use the tissue immediately upon opening the package.

Inventive Principle:
Principle #10Preliminary action

3Reliability

If traditional storage systems are used, then fluid seal maintenance is improved, but system orientation requirements worsen

Engineering Contradiction:
Improvefluid seal maintenanceVSAvoidhandling convenience
Core Design Contradiction:
ReliabilityVSEase of operation

Solution Approach 1:

The packaging system uses flexible membranes and seals that can adapt to different orientations and positions. The fluid reservoir and sealing mechanisms are designed to maintain the fluid seal regardless of how the container is positioned, eliminating orientation requirements while maintaining reliable fluid containment and tissue preservation.

Inventive Principle:
Principle #30Flexible shells and thin films

Data Source

PatentUS12575558B2Packaging system for a medical product
Publication Date: 2026.03.17 AXOGEN CORP
  • US12575558B2 patent drawing
  • US12575558B2 patent drawing
  • US12575558B2 patent drawing

AI summary

A packaging system includes a holder and an inner container. The holder includes a top portion and a bottom portion that cooperate to form a cavity configured to receive one or more medical products therein and to retain the one or more medical products therein. The inner container defines an interior region configured to receive the holder therein. The holder includes sidewalls that form the cavity, and the sidewalls include channels configured to fluidly connect the cavity to the interior region of the inner container.