Tissue Holder Porous Filter for Biopsy Fluid Removal

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Solution Overview

Problem

Fluids present during the biopsy process, such as blood and surgical solutions, interfere with the imaging of tissue samples, reducing the quality of the images and making it difficult to diagnose accurately.

Innovation Solution

The use of a tissue holder assembly with a fluid removal reservoir and a porous filter at the bottom of the tissue storage compartments to remove excess fluid from the imaging field, ensuring that only the tissue sample is imaged.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If tissue samples are transported through a fluid pathway by vacuum during biopsy, then tissue sample collection is efficient and automated, but fluid is deposited into the tissue sample handling apparatus along with the tissue samples, interfering with imaging

Engineering Contradiction:
Improvetissue sample collection efficiencyVSAvoidfluid interference with imaging
Core Design Contradiction:
ProductivityVSObject-affected harmful factors

Solution Approach 1:

The tissue holder is divided into multiple separate storage compartments, each capable of receiving and containing tissue samples independently. This segmentation allows fluid to be managed separately from the tissue samples, with drainage features enabling fluid removal while keeping tissue samples dry and ready for imaging.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

Fluid is extracted and removed from the tissue sample storage environment through drainage features at the bottom of each compartment. This extraction process separates the harmful fluid from the tissue samples, allowing efficient sample collection to continue while preventing fluid interference with subsequent imaging procedures.

Inventive Principle:
Principle #2Taking out (Extraction)

2Productivity

If multiple tissue samples are stored in the same apparatus, then multiple samples can be processed without removing the biopsy device, but fluid accumulates in the storage apparatus, degrading image quality

Engineering Contradiction:
Improvemultiple sample processing capabilityVSAvoidimaging quality
Core Design Contradiction:
ProductivityVSMeasurement precision

Solution Approach 1:

Multiple tissue samples are stored in separately divided compartments within the tissue holder. Each compartment has its own drainage features, ensuring that fluid from one sample does not contaminate other samples. This segmentation maintains imaging quality for each sample while enabling efficient processing of multiple samples in sequence.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The drainage features act as intermediary structures between the tissue samples and the external environment. These features selectively remove fluid while retaining tissue samples in the storage compartments, serving as a mediator that protects sample quality without interfering with the multiple sample processing capability.

Inventive Principle:
Principle #24Intermediary (Mediator)

3Loss of time

If fluid is present in the imaging field during tissue sample imaging, then the imaging process can proceed immediately after sample collection, but the fluid reduces image quality and diagnostic accuracy

Engineering Contradiction:
Improvetime from sample collection to imagingVSAvoiddiagnostic image quality
Core Design Contradiction:
Loss of timeVSMeasurement precision

Solution Approach 1:

The drainage features are designed to automatically remove fluid from tissue samples as they are deposited into the storage compartments, before the samples are moved to the imaging position. This preliminary fluid removal action ensures that samples are ready for immediate high-quality imaging without requiring additional fluid removal steps, thus minimizing time loss while maintaining diagnostic image quality.

Inventive Principle:
Principle #10Preliminary action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This solution effectively reduces fluid interference in the imaging field, resulting in higher-quality images of the tissue samples, which enhances diagnostic accuracy and reduces the need for repeat procedures.

Implementation Method 1

a porous filter at the bottom of the tissue storage compartments to remove excess fluid from the imaging field

Methodology Applied
Scientific EffectCapillary action: Capillary Action

Implementation Method 2

a porous filter at the bottom of the tissue storage compartments to remove excess fluid from the imaging field

Methodology Applied
Scientific EffectFiltration: Filter (physical)

Data Source

PatentUS20250143679A1Devices and methods for reducing fluid in the imaging field of a tissue handling apparatus for improving biopsy system imaging quality
Publication Date: 2025.05.08 HOLOGIC INC
  • US20250143679A1 patent drawing
  • US20250143679A1 patent drawing
  • US20250143679A1 patent drawing

AI summary

A tissue holder assembly for receiving and imaging severed tissue samples from a biopsy device includes a base and a cover removably attached to the base to define an interior, the base having one or more vacuum lumens in communication with the interior, the assembly further including a tissue tray removably and rotatably mounted in the interior, wherein a bottom of the tissue tray comprises a filter material that allows fluid to pass through. The cover has a tissue sample entry port formed therein and configured direct severed tissue samples and fluid aspirated therethrough into a respective tissue storage compartment of the tissue tray positioned under the tissue sample entry port, wherein the base includes a raised surface underlying at least a portion of the tissue tray circumferentially spaced apart from the tissue sample entry port when the cover is attached to the base.