Tissue Illumination System Spectral Contrast Enhancement
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Solution Overview
Problem
Under broadband light, it is difficult for the human eye to distinguish clearly between inflamed and uninflamed tissue regions due to the averaging of spectral signatures, leading to poor contrast between these areas.
Innovation Solution
A tissue illumination system using a combination of radiation in specific wavelength bands, with peak wavelengths between 640 nm and 740 nm for the first band and 470 nm and 530 nm for the second band, and an intensity ratio between 0.2 and 1, to enhance the contrast between inflamed and uninflamed regions by delivering radiation with a spectral full-width-at-half-maximum of 40 nm to 150 nm.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Illumination intensity
If broadband light is used to illuminate tissue, then the tissue is evenly illuminated, but the contrast between inflamed and uninflamed regions deteriorates due to spectral averaging
Solution Approach 1:
The broadband spectrum is segmented into multiple discrete wavelength bands (e.g., 450-480nm, 560-590nm, 630-660nm, 780-810nm). Instead of using continuous broadband light, the system divides the spectrum into distinct segments that can be independently controlled and combined to enhance specific tissue contrasts while maintaining overall illumination.
Solution Approach 2:
Different wavelength bands are selectively applied to highlight different tissue properties. The system uses specific wavelength ranges that interact differently with blood-rich versus non-blood-rich tissue, creating local spectral quality variations that enhance the visibility of inflamed regions without compromising overall illumination uniformity.
2Measurement precision
If the spectral bandwidth is narrowed to improve contrast, then the distinction between tissue regions improves, but the illumination coverage and versatility deteriorate
Solution Approach 1:
Multiple narrow bandwidth LED sources with different peak wavelengths are merged into a single illumination system. Each LED provides a narrow spectral band optimized for specific tissue contrast, while the combination of multiple LEDs achieves broad spectral coverage and versatile illumination capabilities across different tissue types and conditions.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
This approach allows for better visibility and distinction between inflamed and uninflamed tissue regions, improving the perceived contrast and enabling clearer identification of bruises, spots, and other skin lesions.
Implementation Method 1
at least one radiation source configured to generate: first radiation in a first wavelength band at a first intensity, the first radiation having a peak wavelength, λ 1 ; and second radiation in a second wavelength band at a second intensity, the second radiation having a peak wavelength, λ 2
Data Source
Figure 1(a)~1(f)
Figure 2(a)~2(d)
Figure 3(a)~3(c)
AI summary
The invention discloses a tissue illumination system (700). The tissue illumination system (700) includes at least one radiation source (702) configured to generate first radiation in a first wavelength band at a first intensity, the first radiation having a peak wavelength, λ1; and second radiation in a second wavelength band at a second intensity, the second radiation having a peak wavelength, λ2. An intensity ratio of the first intensity relative to the second intensity is between 0.2 and 1; and the peak wavelength λ1 of the first wavelength band and the peak wavelength λ2 of the second wavelength band are selected such that they satisfy the following relationships: Formula (I). The tissue illumination system (700) also includes a radiation delivery unit (404) configured to deliver the first radiation and the second radiation towards tissue of a subject. An optical filter system, a device, a tissue illumination method and a computer program product are also disclosed.