Tissue Injury Index Calculation from Medical Imaging Data

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Solution Overview

Problem

Current methods fail to accurately predict which multiply injured patients are at risk for systemic inflammation and organ failure, as they lack a reliable metric to quantify tissue damage from medical imaging data.

Innovation Solution

An analytical system and method that calculates a tissue injury index by measuring the volume of tissue damage from medical images, using a computing device to identify and quantify tissue injuries, and determining the risk of systemic inflammation and organ failure based on the total volume of tissue injury.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If traditional clinical assessment methods are used to evaluate tissue damage, then the assessment process is simple and quick, but the prediction accuracy for systemic inflammation and organ failure is insufficient

Engineering Contradiction:
Improveprediction accuracyVSAvoidassessment complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent replaces traditional mechanical/clinical assessment methods with an automated image processing system that uses computational algorithms to analyze medical images and calculate tissue damage volume, thereby improving measurement precision while managing complexity through automation

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The patent introduces a computational model and image processing software as intermediaries between the medical images and clinical decision-making, enabling accurate tissue damage quantification that bridges the gap between imaging data and clinical prediction needs

Inventive Principle:
Principle #24Intermediary (Mediator)

2Reliability

If a reliable metric for tissue damage quantification is implemented, then the ability to predict systemic inflammation and organ failure is improved, but the complexity of the analysis system increases

Engineering Contradiction:
Improverisk prediction reliabilityVSAvoidsystem complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent segments the complex analysis task into distinct components: image acquisition, image processing, tissue damage identification, volume calculation, and risk prediction, allowing each component to be optimized independently while maintaining overall system reliability

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent transforms qualitative clinical assessment into quantitative measurement by changing the parameter from subjective clinical evaluation to objective tissue damage volume measurement, thereby improving reliability through standardized metric

Inventive Principle:
Principle #35Parameter changes

3Measurement precision

If manual assessment of tissue damage is performed, then the equipment requirements are minimal, but the measurement precision and consistency are insufficient

Engineering Contradiction:
Improvetissue damage measurement precisionVSAvoidsystem implementation ease
Core Design Contradiction:
Measurement precisionVSEase of manufacture

Solution Approach 1:

The patent uses digital copying of medical images and creates virtual models of tissue damage, allowing precise measurement without physical manipulation of specimens, thereby improving measurement precision while maintaining ease of implementation through software-based solutions

Inventive Principle:
Principle #26Copying

Data Source

PatentUS11211166B2Methods and systems for tissue damage identification and quantification
Publication Date: 2021.12.28 INDIANA UNIVERSITY RESEARCH & TECHNOLOGY CORP
  • US11211166B2 patent drawing
  • US11211166B2 patent drawing
  • US11211166B2 patent drawing

AI summary

Example embodiments are described that relate to the analysis of tissue damage in an injured patient. Example embodiments are methods and systems for collecting medical imaging data, identifying tissue damage in the medical imaging data, analyzing the tissue damage shown in the medical imaging data, and/or quantifying the tissue damage shown in the medical imaging data. The disclosed methods allow for determining a risk for multiple organ failure and systemic inflammation in a multiply injured patient.