Endoscopic Tissue Inversion Using Shape-Memory Clamping

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Solution Overview

Problem

Current endoscopic tissue inversion and resection systems face challenges in effectively inverting and retaining tissue in a plicated configuration for precise resection procedures.

Innovation Solution

The system employs a pair of clamping tubes with shape-memory clamp components and/or magnets that advance to clamp and retain tissue in a plicated configuration, utilizing a guide extension for precise placement and alignment.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If a tissue inversion and resection system is implemented, then tissue resection capability is improved, but device complexity increases

Engineering Contradiction:
Improvetissue resection capabilityVSAvoiddevice complexity
Core Design Contradiction:
ProductivityVSDevice complexity

Solution Approach 1:

The system employs nested clamping tubes where inner tubes can slide within outer tubes, allowing multiple clamping zones to be integrated in a compact configuration. This nesting approach enables complex tissue manipulation functions while maintaining a relatively compact overall device structure, thus improving tissue resection capability without proportionally increasing device complexity.

Inventive Principle:
Principle #7Nested doll (Nesting)

Solution Approach 2:

The device is divided into multiple functional segments including separate clamping tubes, magnets, and shape-memory components that can be independently controlled. This segmentation allows each component to perform its specific function efficiently, improving overall tissue resection capability while enabling modular design that manages device complexity through functional decomposition.

Inventive Principle:
Principle #1Segmentation

2Reliability

If shape-memory clamp components and magnets are used to clamp tissue, then tissue retention in plicated configuration is improved, but device complexity increases

Engineering Contradiction:
Improvetissue retentionVSAvoiddevice complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

Shape-memory alloy components are utilized that automatically return to their original configuration when heated by body temperature, providing self-actuating clamping action without requiring external actuators. This self-service mechanism improves tissue retention reliability while reducing the complexity of control systems needed to operate the clamp components.

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

Magnetic components replace traditional mechanical actuation systems for tissue clamping. Magnets provide holding force through magnetic attraction without requiring complex mechanical linkages, gears, or motors, thus improving tissue retention while simplifying the overall device architecture by substituting electromagnetic principles for mechanical systems.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

3Manufacturing precision

If clamping tubes advance clamp components along opposing sides of plicated tissue, then clamping precision is improved, but device complexity increases

Engineering Contradiction:
Improveclamping precisionVSAvoiddevice complexity
Core Design Contradiction:
Manufacturing precisionVSDevice complexity

Solution Approach 1:

Guide extensions serve as intermediary components that channel and direct clamp components along precise pathways from the clamping tubes to the tissue. These guide structures ensure accurate positioning and alignment of clamping elements without requiring complex active control systems, thus improving clamping precision while managing device complexity through passive geometric constraints.

Inventive Principle:
Principle #24Intermediary (Mediator)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This solution enables efficient tissue inversion and retention, allowing for precise resection while minimizing tissue damage and promoting effective healing.

Implementation Method 1

A shape-memory material may be advanced out of the distal end of the first clamping tube and into the distal end of the second clamping tube... the shape-memory clamp component may have a bend portion that forms a bend at the distal end of the plicated tissue to clamp the plicated tissue

Methodology Applied
Scientific EffectShape memory effect: Shape Memory Alloy

Implementation Method 2

A plurality of magnets may be advanced out of the distal ends of the first clamping tube and second clamping tube... to clamp and retain the tissue in a plicated configuration

Methodology Applied
Scientific EffectMagnetic force: Magnetism

Data Source

PatentUS12303115B2Endoscopic tissue inversion and resection system and method of resecting tissue
Publication Date: 2025.05.20 UNIV OF MIAMI
  • US12303115B2 patent drawing
  • US12303115B2 patent drawing
  • US12303115B2 patent drawing

AI summary

An endoscopic tissue inversion and resection system employs an exemplary endoscopic tissue inversion and resection device configured to invert tissue to plicate the tissue between a pair of clamping tubes that advance a clamp component and guide clamp components around the plicated tissue. A clamp component may include magnets and/or a shape memory material. The magnets may produce a pinching force of the tissue. A shape-memory clamp component may have a preform shape that when configured around the plicated tissue clamps and retains the plicated tissue. An endoscope is configured between the first clamping tube and a second clamping tube and a tissue grasping device plicates the tissue. The endoscope may have an imaging device, to enable viewing of the interior of the body during a procedure to guide the endoscope to a desired location.