Tissue Joining Device Fluid Removal and Energy Output

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Solution Overview

Problem

Existing medical treatment devices face challenges in effectively joining body tissues due to the strong polarity of water molecules, which interferes with the hydrogen bonding between proteins, making tissue conjugation difficult.

Innovation Solution

A medical treatment device with a pair of holding members and an energy output portion that supplies energy to the tissues, along with a conjugation maintenance assistance portion to prevent fluid infiltration, ensuring a stable joined state by applying a substance that prevents fluid infiltration and maintains the joined tissues.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If energy is supplied to denature proteins and remove fluid to join tissues, then tissue conjugation is achieved, but water molecules interfere with hydrogen bonding between proteins making conjugation difficult

Engineering Contradiction:
Improvetissue conjugationVSAvoidwater molecule interference
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent applies preliminary action by first removing fluid from the treatment area before applying energy to denature proteins. The fluid removal portion extracts water molecules that would interfere with hydrogen bonding, creating favorable conditions for subsequent protein conjugation. This sequential approach ensures that water interference is eliminated before the conjugation process begins.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The patent segments the treatment device into distinct functional portions: a fluid removal portion and an energy output portion. This segmentation allows each component to perform its specific function optimally - the fluid removal portion eliminates water molecules, while the energy output portion denatures proteins and enables conjugation. The separated functions address the water interference problem systematically.

Inventive Principle:
Principle #1Segmentation

2Strength

If energy is supplied to raise tissue temperature for protein denaturation, then conjugation is promoted, but fluid infiltration prevents stable joined state

Engineering Contradiction:
Improvejoined state stabilityVSAvoidfluid infiltration
Core Design Contradiction:
StrengthVSObject-generated harmful factors

Solution Approach 1:

The patent applies preliminary action by removing fluid from the treatment area before energy application. The fluid removal portion operates first to extract water molecules that would otherwise infiltrate the joining area and prevent stable conjugation. This preparatory step ensures that when energy is applied and proteins are denatured, no fluid remains to interfere with the joined state stability.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The patent introduces a fluid removal portion as an intermediary component between the tissue and the energy output portion. This intermediary element actively removes water molecules that would interfere with the conjugation process, creating an optimal environment for stable tissue joining. The fluid removal portion acts as a mediator that eliminates harmful factors before the main conjugation action occurs.

Inventive Principle:
Principle #24Intermediary (Mediator)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The device effectively joins body tissues by denaturing proteins and removing fluid, allowing for reliable contact and long-term maintenance of the joined state, preventing fluid infiltration and enhancing tissue conjugation efficiency.

Implementation Method 1

denaturing proteins denotes inducing a conformational change, which is one of features of proteins, that is, dissociating the linkage of polar groups linked with certain regularity to form the conformational structure of proteins

Methodology Applied
Scientific EffectProtein denaturation:

Implementation Method 2

the temperature of joining target tissues is raised to denature proteins and to remove moisture (H2O) present between target tissues simultaneously

Methodology Applied
Scientific EffectEvaporation: Evaporation

Implementation Method 3

body tissues can be joined by (1) bringing body tissues to be joined into contact, (2) denaturing proteins of target tissues, and (3) removing fluid present between target tissues. This is join using a so-called hydrogen bond, which is a linkage using polarity of a polar group of amino acids constituting proteins

Methodology Applied
Scientific EffectHydrogen bonding:

Data Source

PatentUS9907605B2Medical treatment device, medical treatment system, and medical treatment method
Publication Date: 2018.03.06 OLYMPUS CORPORATION(JP)
  • US9907605B2 patent drawing
  • US9907605B2 patent drawing
  • US9907605B2 patent drawing

AI summary

A medical treatment device to treat and join body tissues, includes at least a pair of holding members which is configured to hold the body tissues to be treated, an energy output portion provided on at least one of the pair of holding members and connected to an energy source to form a joined portion by supplying energy to the body tissues held by the pair of holding members to join the body tissues, and a join condition maintenance assistance portion capable of applying a substance which prevents infiltration of the fluid to the body tissues to be treated to provide assistance so that a joined state of the body tissues is maintained.