Tissue Storage Packaging With Cradle Immersion and Drainage
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Solution Overview
Problem
Existing tissue storage methods require specialized refrigeration equipment and complicate transportation and usage due to supply and logistic constraints, limiting facilities that can utilize tissue grafts.
Innovation Solution
A packaging system with a cavity and tissue cradles of varying sizes, allowing immersion and drainage of tissue specimens in a liquid medium, and a sealable design for convenient handling and storage.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Duration of action of stationary object
If specialized refrigeration equipment is used to store tissue at extremely low temperature, then tissue storage life is extended, but device complexity and ease of operation deteriorate due to requiring specialized equipment and complicating transportation
Solution Approach 1:
The patent changes the storage temperature parameter from extremely low temperatures requiring refrigeration to refrigeration-free conditions, allowing tissue storage at higher temperatures while maintaining tissue viability through the use of preservative solutions and controlled packaging environments
Solution Approach 2:
The patent extracts the refrigeration requirement from the tissue storage system by using preservative solutions and packaging designs that maintain tissue integrity without cold temperatures, eliminating the need for specialized refrigeration equipment
2Duration of action of stationary object
If specialized refrigeration equipment is used for tissue storage, then tissue storage life is extended, but ease of operation worsens due to complicating transportation to end-use facilities
Solution Approach 1:
The patent changes the storage temperature parameter from cold chain requirements to ambient temperature storage, enabling standard transportation methods without specialized refrigerated vehicles or containers, thus improving transportation convenience while maintaining tissue storage life
Solution Approach 2:
The patent removes the refrigeration dependency from the tissue storage and transportation system by using preservative solutions that maintain tissue viability at higher temperatures, eliminating the need for cold chain logistics and simplifying transportation operations
3Duration of action of stationary object
If tissue is stored in preservative solution, then storage life is prolonged, but device complexity increases due to requiring fluidly sealed packaging with tissue cradles
Solution Approach 1:
The packaging structure serves multiple functions simultaneously: the cavity provides containment, the tissue cradle supports and positions the tissue specimen, the seal ensures fluid tightness, and the integrated design eliminates the need for separate refrigeration components, making the complex structure worthwhile for its multi-functionality
4Duration of action of stationary object
If tissue is stored in preservative solution, then storage life is prolonged, but ease of operation worsens due to requiring specialized handling procedures
Solution Approach 1:
The tissue cradle is designed to automatically support and position the tissue specimen within the preservative solution without requiring complex handling procedures, allowing the packaging system to serve itself by maintaining tissue integrity through its inherent structural design rather than requiring specialized handling operations
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
Facilitates convenient transport and storage of tissues by maintaining tissue integrity and ease of manipulation, reducing the need for specialized equipment and enhancing storage life.
Implementation Method 1
The tissue cradle may be configured to allow the liquid to drain from the tissue cradle upon removal from the cavity. The tissue cradle may include one or more openings to allow the liquid to drain from the tissue cradle upon removal from the cavity.
Implementation Method 2
a seal configured to be joined to the packaging body to fluidly seal the cavity
Implementation Method 3
The tissue cradle is configured to support a tissue specimen. The tissue cradle may be configured to at least partially immerse a tissue specimen supported in the tissue cradle in a liquid disposed in the cavity.
Data Source
Figure 1A~1B
Figure 2A~2B
Figure 3A~3B
AI summary
A packaging system (10b) is provided that includes a packaging body defining a cavity (14b) and a seal (18b) configured to be joined to the packaging body to fluidly seal the cavity. The packaging system may also include at least one tissue cradle (16b) configured to be disposed within the cavity. A cavity having a single size may be configured to accommodate differently sized tissue cradles. In addition to the cavity the packaging system may include one or more additional reservoirs configured for holding a volume of liquid. Such packaging systems may be used in the storage of wet-preserved or dry-preserved human or animal tissue. Also provided are a packaged tissue specimen and a method for packaging tissue.