Tissue Placement Device for Minimally Invasive Ovarian Reimplantation

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Solution Overview

Problem

Current methods for reimplanting ovarian tissue in patients undergoing oncological therapy are invasive, carry significant surgical risks, and result in substantial psychological and aesthetic impacts on patients.

Innovation Solution

A device for the placement of organic tissue, comprising a hollow tubular base element with a primary duct to house the tissue, which can be used for both percutaneous and endoscopic procedures, minimizing tissue trauma and avoiding the need for extensive surgical incisions.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If transcutaneous incisional approach is used for ovarian tissue reimplantation, then tissue placement is achieved, but surgical risks and psychological impact increase

Engineering Contradiction:
Improvesurgical safetyVSAvoidpsychological impact
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The device divides the tissue placement process into separate functional components: a delivery catheter for inserting ovarian tissue, a scrotal prosthesis for providing a receiving chamber, and a testicular prosthesis for structural support. This segmentation allows minimally invasive delivery while distributing the surgical burden across multiple components, reducing overall surgical risk and psychological impact.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The device introduces intermediate structures (delivery catheter, scrotal prosthesis) that mediate between the surgical site and the ovarian tissue placement. These intermediaries enable minimally invasive delivery through the scrotal wall while providing protected receiving chambers, thereby reducing direct tissue trauma and psychological stress on patients.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Reliability

If laparotomic/endoscopic approach is used for ovarian tissue reimplantation, then tissue placement is achieved, but hospitalization and costs increase

Engineering Contradiction:
Improvetissue placement successVSAvoidhospitalization time
Core Design Contradiction:
ReliabilityVSLoss of time

Solution Approach 1:

The device extracts the ovarian tissue placement function from complex laparotomic or endoscopic procedures and delivers it through a simplified percutaneous scrotal approach. The delivery catheter can be inserted through a small scrotal incision, eliminating the need for extensive abdominal surgery and reducing hospitalization requirements while maintaining placement success.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The device employs disposable, single-use components (delivery catheter, scrotal prosthesis) that eliminate the need for expensive, complex reusable surgical instruments. This approach reduces procedural costs and shortens hospitalization time while ensuring reliable tissue placement through the specialized disposable system.

Inventive Principle:
Principle #27Cheap short-living objects (Disposable)

3Reliability

If conventional surgical methods are used for ovarian tissue reimplantation, then tissue placement is achieved, but aesthetic outcome deteriorates

Engineering Contradiction:
Improvetissue placement accuracyVSAvoidaesthetic result
Core Design Contradiction:
ReliabilityVSShape

Solution Approach 1:

The device applies local quality changes by placing the receiving chamber and structural support specifically within the scrotal and testicular regions rather than requiring abdominal surgery. This localized approach maintains the natural appearance of the scrotum and testes while providing accurate ovarian tissue placement, thereby preserving aesthetic outcomes.

Inventive Principle:
Principle #3Local quality

Solution Approach 2:

Instead of approaching the ovarian tissue placement from the abdominal cavity (laparotomy) or requiring large incisions, the device inverts the approach by delivering tissue through the scrotal wall from the outside. This inverted percutaneous approach minimizes visible scarring and preserves aesthetic appearance while maintaining placement accuracy.

Inventive Principle:
Principle #13The other way round (Inversion)

4Reliability

If minimally invasive approach is used for tissue placement, then surgical risks are reduced, but device complexity increases

Engineering Contradiction:
Improvesurgical safetyVSAvoiddevice structure
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The device employs a nested structure where the delivery catheter can be inserted through the scrotal wall, with the scrotal prosthesis and testicular prosthesis forming nested chambers within the scrotal space. This nesting allows minimally invasive delivery while organizing complex components in a compact, manageable arrangement that reduces operational complexity.

Inventive Principle:
Principle #7Nested doll (Nesting)

Solution Approach 2:

The device achieves multi-functionality through the scrotal prosthesis, which serves as both a structural support element and a receiving chamber for ovarian tissue, while the testicular prosthesis provides additional structural support. This universal design reduces the number of separate components needed, simplifying the overall device while maintaining surgical safety.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Data Source

PatentUS20250127539A1Device for the Placement of Organic Tissue and Relative Apparatus
Publication Date: 2025.04.24 ALMA MATER STUDIORUM UNIV DI BOLOGNA
  • US20250127539A1 patent drawing
  • US20250127539A1 patent drawing
  • US20250127539A1 patent drawing

AI summary

A device for the placement of organic tissue, in particular endocrine tissue, includes a hollow tubular base element configured to house in a seat at least one portion of the organic tissue, a pushing element which inserted on the inside of the base element and coupled to it in a sliding manner; wherein the base element is configured to at least partially penetrate a target tissue. The base element further includes a first opening, which is arranged in a distal zone towards a first end and is configured to let out and, hence, position the organic tissue in the target tissue through the action of the pushing element.