Tissue Retrieval Device with Pressure-Applying Mechanism
Find Innovative SolutionsGenerate Solutions
Solution Overview
Problem
Conventional medical devices, such as endoscopes and duodenoscopes, face challenges in navigating deep anatomical regions, obtaining sufficient tissue samples, and incorporating steerability and tissue collection features in small-diameter devices, particularly in procedures like ERCP, where multiple insertions and reinsertions are necessary to collect adequate sample material.
Innovation Solution
The development of tissue retrieval devices with pressure-applying mechanisms that allow deeper penetration and collection of larger sample volumes, using elongate bodies with tissue separators and collectors, and methods involving the use of auxiliary scopes and control mechanisms to facilitate sample collection through small-diameter passages.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Volume of moving object
If conventional endoscopes are used to navigate deep anatomical regions, then access to difficult-to-reach locations is achieved, but the ability to obtain sufficient tissue sample sizes is limited
Solution Approach 1:
The tissue retrieval device is inserted through the working channel of the endoscope, which itself is inserted into the patient's anatomy. This nested configuration allows the tissue collection device to reach deep anatomical regions while maintaining the capability to collect sufficient tissue samples, as the device expands or extends at the distal end to perform tissue retrieval.
Solution Approach 2:
The tissue retrieval device incorporates movable components such as the elevator mechanism that can be actuated to extend or deploy the tissue collection elements. This dynamic capability allows the device to transition from a compact insertion state to an expanded tissue retrieval state, enabling sufficient sample collection while maintaining navigability through the endoscope's working channel.
2Ease of operation
If small-diameter devices are used to access deep anatomical regions, then navigation through tight spaces is improved, but the ability to incorporate steerability and tissue collection features is reduced
Solution Approach 1:
The tissue retrieval device with its full array of features (steerability mechanisms, tissue collection elements, elevator) is nested within the endoscope's working channel during insertion. This allows the complete functional device to access deep anatomical regions through the small-diameter endoscope while maintaining all necessary tissue collection and manipulation capabilities at the distal end.
Solution Approach 2:
The tissue retrieval device is divided into functional segments including the elongate body, tissue collection elements, and actuation mechanisms. This segmentation allows each component to be optimized for its specific function while fitting within the constraints of the endoscope's working channel diameter, enabling both navigation ease and tissue collection versatility.
3Productivity
If conventional tissue retrieval devices are used, then insertion through endoscope working channels is achieved, but the time and cost of repeatedly removing and reinserting devices to obtain sufficient sample material increases
Solution Approach 1:
The tissue retrieval device is designed with sufficient tissue collection capacity from the outset, incorporating features such as the elevator mechanism and appropriately sized collection elements that can obtain adequate tissue samples in a single insertion. This preliminary design consideration eliminates the need for repeated insertions and removals, thereby reducing procedure time and associated costs.
Solution Approach 2:
The device enables continuous tissue collection during a single insertion procedure, allowing the operator to retrieve multiple samples or sufficient tissue volume without interrupting the procedure by removing and reinserting the device. This continuous action improves productivity and reduces the time loss associated with repeated manipulations.
Data Source
AI summary
A tissue separation device can comprise an elongate body comprising a proximal end portion and a distal end portion, a tissue separator coupled to the distal end portion, the tissue separator configured to engage sample tissue for retrieval, and a pressure-applying device configured to bias the tissue separator against the sample tissue. A method of collecting biological matter using a tissue retrieval device can comprise inserting the tissue retrieval device into anatomy of a patient, guiding a tissue collector of the tissue retrieval device to a target tissue area, activating a pressure applying device to bias the tissue collector into the target tissue, and collecting biological matter with the tissue retrieval device.