Tissue Scaffold with Variable Yarn Diameter Textile

Solution Overview

Problem

Current artificial ligaments for tendon or ligament reconstruction lack mechanical strength and tissue compatibility, leading to adverse reactions, integration issues, and long-term failure due to wear and tear.

Innovation Solution

A tissue scaffold is designed with a textile structure formed by interweaving warp yarns of varying diameters in different regions, creating areas with varying porosity and mechanical strength to support cell attachment and growth, while maintaining structural stability.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Strength

If artificial ligaments are designed to provide mechanical strength, then structural integrity is improved, but tissue compatibility and integration with surrounding tissues deteriorate

Engineering Contradiction:

Improvemechanical strengthVSAvoidtissue compatibility

Core Design Contradiction:

StrengthVSAdaptability or versatility

Solution Approach 1:

The textile structure incorporates regions with different yarn diameters (first diameter and second diameter) to create zones with varying mechanical properties and porosity. This local differentiation allows certain regions to provide enhanced mechanical strength while other regions facilitate cell attachment and tissue integration, resolving the contradiction between overall strength and local tissue compatibility.

Inventive Principle:

Principle #3Local quality

Solution Approach 2:

The invention uses a composite textile structure combining yarns of different diameters and materials within a single scaffold. This composite approach enables the scaffold to simultaneously exhibit high mechanical strength from denser yarn regions and良好的 tissue compatibility from more porous regions, allowing both requirements to be met within the same structure.

Inventive Principle:

Principle #40Composite materials

2Stability of the object's composition

If artificial ligaments focus on mechanical strength repairs, then structural stability is improved, but ability to integrate with surrounding tissues deteriorates

Engineering Contradiction:

Improvestructural stabilityVSAvoidintegration ability

Core Design Contradiction:

Stability of the object's compositionVSAdaptability or versatility

Solution Approach 1:

The textile structure incorporates regions with different yarn diameters (first diameter and second diameter) to create zones with varying mechanical properties and porosity. This local differentiation allows certain regions to provide enhanced mechanical strength while other regions facilitate cell attachment and tissue integration, resolving the contradiction between overall strength and local tissue compatibility.

Inventive Principle:

Principle #3Local quality

Solution Approach 2:

The scaffold employs a porous textile structure with controlled pore sizes created by the interweaving pattern of yarns with different diameters. These pores enable cell infiltration, nutrient transport, and tissue ingrowth, significantly improving integration ability while the overall textile architecture maintains structural stability through its woven configuration.

Inventive Principle:

Principle #31Porous materials

3Adaptability or versatility

If pore size is increased to allow cell growth, then tissue compatibility is improved, but mechanical strength deteriorates

Engineering Contradiction:

Improvetissue compatibilityVSAvoidmechanical strength

Core Design Contradiction:

Adaptability or versatilityVSStrength

Solution Approach 1:

The textile structure incorporates regions with different yarn diameters (first diameter and second diameter) to create zones with varying mechanical properties and porosity. This local differentiation allows certain regions to provide enhanced mechanical strength while other regions facilitate cell attachment and tissue integration, resolving the contradiction between overall strength and local tissue compatibility.

Inventive Principle:

Principle #3Local quality

Solution Approach 2:

The invention uses a composite textile structure combining yarns of different diameters and materials within a single scaffold. This composite approach enables the scaffold to simultaneously exhibit high mechanical strength from denser yarn regions and良好的 tissue compatibility from more porous regions, allowing both requirements to be met within the same structure.

Inventive Principle:

Principle #40Composite materials

Data Source

PatentUS20250205038A1Tissue scaffold and method of manufacturing the same

Publication Date: 2025.06.26 IND TECH RES INST

AI summary

A tissue scaffold is provided. The tissue scaffold includes a textile formed by interweaving a plurality of warp yarns and a plurality of weft yarns. The textile includes a first region and a second region, and the second region is adjacent to the first region. The plurality of warp yarns have different diameters in the first region and the second region. The textile has a plurality of pores, and the size of each of the plurality of pores is between 100 μm and 800 μm. A method of manufacturing the aforementioned tissue scaffold is also provided.