Tissue Sensing Data Virtual Representation for Biopsy Analysis

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Solution Overview

Problem

Current medical procedures for tissue characterization, such as biopsies, are invasive and rely heavily on lab tests and imaging, which are not always definitive, necessitating a more effective method for real-time tissue analysis during procedures.

Innovation Solution

A system that processes tissue sensing data from sensors measuring optical, acoustic, and electrical properties to generate and display two-dimensional tissue characteristic parameters in a graphical interface, enabling real-time decision-making during biopsies, with features for data storage, comparison to known tissue types, and user input for customized display.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If traditional biopsy procedures are used to characterize tissue, then definitive diagnosis can be obtained through lab tests and imaging, but the procedure is invasive and requires extensive tissue sampling

Engineering Contradiction:
Improvediagnostic accuracyVSAvoidinvasiveness and tissue damage
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent replaces mechanical tissue sampling (biopsy needles, surgical excision) with optical sensing systems that use light interaction to characterize tissue properties. Optical sensors detect tissue characteristics through non-contact or minimally invasive means, substituting the mechanical extraction and laboratory analysis approach with real-time optical measurement and analysis systems.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The patent introduces optical sensors as an intermediary between the tissue and the diagnostic system. These sensors act as mediators that interact with tissue optically to extract diagnostic information without requiring physical removal or extensive manipulation of the tissue, thereby reducing invasiveness while maintaining diagnostic capability.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Loss of information

If multiple lab tests and imaging procedures are performed to characterize tissue, then comprehensive diagnostic information can be obtained, but the process is time-consuming and complex

Engineering Contradiction:
Improvecompleteness of diagnostic informationVSAvoidtime for diagnosis and treatment decision
Core Design Contradiction:
Loss of informationVSLoss of time

Solution Approach 1:

The patent combines multiple diagnostic functions into a single integrated optical sensing system. The system simultaneously performs multiple measurements (absorbance, fluorescence, scattering) and integrates the data processing and analysis functions within one device, eliminating the need for separate lab tests and imaging procedures while maintaining comprehensive diagnostic information.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The patent enables continuous real-time monitoring and analysis of tissue properties during the examination procedure. The optical sensing system continuously collects data and provides immediate feedback, allowing for ongoing diagnostic assessment without interruption or delay, as opposed to discrete, sequential lab tests that require sample processing time.

Inventive Principle:
Principle #20Continuity of useful action

3Productivity

If real-time tissue analysis is implemented during biopsy procedures, then on-spot decision-making is enabled, but the system complexity increases

Engineering Contradiction:
Improvespeed of diagnostic decision-makingVSAvoidsystem complexity
Core Design Contradiction:
ProductivityVSDevice complexity

Solution Approach 1:

The patent incorporates pre-programmed analysis algorithms and reference databases within the system that automatically compare real-time optical measurements against known tissue characteristics. This preliminary preparation of analysis routines and reference data enables immediate interpretation of measurements without requiring complex manual analysis or external processing, thus achieving real-time decision-making with manageable system complexity.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The system performs self-diagnosis through automated data processing and interpretation algorithms that independently analyze the optical sensor readings and generate diagnostic conclusions. The built-in processing capabilities allow the system to serve its own analytical needs without requiring external laboratory infrastructure or complex manual intervention, enabling real-time decisions while keeping the system relatively simple.

Inventive Principle:
Principle #25Self-service

Data Source

PatentUS12064271B2Tissue properties presentation system and method
Publication Date: 2024.08.20 DILON MEDICAL TECH LTD
  • US12064271B2 patent drawing
  • US12064271B2 patent drawing
  • US12064271B2 patent drawing

AI summary

System and method for presentation of tissue sensing data being collected from a tissue being measured are presented and configured for on-line as well as for off-line presentation of the tissue sensing data, the system comprising a device configured and operable to display a graphical user interface, the graphical user interface comprises at least one observation field and is configured to be responsive to the tissue sensing data comprising one or more sensing datum of measured tissue property value, to transform each measured tissue property value into virtual representation in the at least one observation field in the form of a parametric space of two different characteristic parameters of tissue corresponding to the measured tissue property value.