Motor-Driven Tissue Slicing Device with Filter and Cutter
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Solution Overview
Problem
Current tissue slicing methods are labor-intensive and prone to contamination, relying heavily on operator proficiency and resulting in variable tissue sizes, especially when processing large quantities, with contamination often not detected until the final culturing stage.
Innovation Solution
A tissue slicing device comprising a motor-driven filling assembly with a filter and cutter, utilizing a piston rod to push tissue through a filter with conical protrusions and a movable blade or ultrasonic/laser cutter for precise slicing, integrated with a rotating plate and elastic locking mechanism to automate the process and ensure consistent tissue size.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Extent of automation
If manual tissue slicing is performed by human operators, then flexibility and adaptability are maintained, but labor intensity increases and contamination risk rises
Solution Approach 1:
The device is divided into independent functional modules: a filling assembly for loading tissue samples, a slicing assembly with cutter and guiding body for tissue slicing, and a collection assembly for receiving sliced tissues. This modular segmentation enables automated operation while keeping each module's structure relatively simple and manageable.
Solution Approach 2:
The slicing device is designed as a multi-functional integrated system that combines filling, slicing, and collection functions into one apparatus. The guiding body with adjustable guiding holes can accommodate different tissue sizes and slicing requirements, making the device universally applicable for various tissue slicing tasks without requiring multiple separate tools.
2Productivity
If multiple tissue samples are processed by one operator, then productivity increases, but operation time per sample increases and contamination risk increases
Solution Approach 1:
The filling assembly allows continuous loading of multiple tissue samples into the tube, and the slicing assembly continuously processes samples through automated cutting. The guiding body with multiple guiding holes enables simultaneous or sequential processing of multiple samples without requiring repositioning or resetting between samples, maintaining continuous productive action and reducing idle time.
3Manufacturing precision
If tissue slicing is performed manually to avoid contamination, then contamination control is maintained, but the size uniformity of sliced tissue decreases
Solution Approach 1:
The guiding body acts as an intermediary component between the tissue sample and the cutter. It provides precisely positioned guiding holes that constrain the tissue to specific locations and orientations during slicing. This intermediary structure ensures uniform slice sizes through geometric precision while the closed-tube filling assembly maintains contamination control, resolving the conflict between precision and contamination prevention.
4Ease of operation
If automated slicing is implemented, then labor requirements decrease, but the initial device complexity and cost increase
Solution Approach 1:
The device is designed to be self-sufficient in its automated operation. The filling assembly automatically loads tissue into the tube, the slicing assembly autonomously performs cutting operations through the guiding body, and the collection assembly automatically receives and organizes sliced tissues. Once set up, the system operates with minimal human intervention, making the initial complexity worthwhile by providing ease of operation for subsequent use.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The device automates the tissue slicing process, reducing manpower and time while minimizing contamination, ensuring consistent tissue size and efficiency in primary cell isolation, allowing for larger quantities to be processed with reduced operator dependency.
Implementation Method 1
the tissue in the tube is pushed by the piston rod so the tissue is squeezed and separated through each of the pores of the filter
Implementation Method 2
The cutter comprises a blade and a second motor connected to the blade, and the blade is moveable back and forth
Data Source
AI summary
Provided is a tissue slicing device having a first motor, a filling assembly, a filter, a pipe, and a cutter. The filling assembly includes a tube and a piston rod movably inserted through the tube. One end of the piston rod abuts against the first motor. The filter is located at an end of the tube opposite the first motor. The pipe is located at a common side of the first motor and the filling assembly, and includes a nozzle located at an end of the pipe and proximal to an end of the filter opposite the filling assembly. The cutter is proximal to the filter. The guiding body is located at the end of the tube opposite the first motor. Provided is an apparatus having the tissue slicing device, such that manpower and time can be saved, and the tissue slicing degree can be unified.