Tissue Transfer Device with Expandable Separators for Regeneration
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Solution Overview
Problem
Conventional tissue rejuvenation procedures often result in less-than-optimum results and scarring due to the limitations of existing methods for repairing, regenerating, or renewing body tissues affected by injury, disease, wear, aging, or other causes.
Innovation Solution
A tissue transfer device comprising a cannula with expandable tissue separating members, a tissue reservoir, and a pump, which allows for the removal of tissue regenerative cells from a cell harvest site and their mechanical agitation and injection at a cell injection site, facilitating the recruitment of resident and bone-marrow derived cells for tissue repair and regeneration without inducing apoptosis.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If conventional tissue rejuvenation procedures are used, then tissue repair and regeneration can be achieved, but scarring and less-than-optimum results occur
Solution Approach 1:
The tissue separating members divide the tissue into discrete segments or compartments, allowing for controlled cell harvest and injection pathways that minimize traumatic disruption to surrounding tissue structures, thereby reducing scarring while maintaining effective tissue regeneration
Solution Approach 2:
The device introduces an intermediary mechanical system (cannula with tissue separating members) that facilitates cell transfer through a controlled pathway, replacing direct invasive techniques with a mediated process that reduces tissue trauma and scarring while achieving the desired regeneration effect
2Ease of operation
If tissue separating members are deployed to separate tissue portions, then cell harvest and injection are facilitated, but device complexity increases
Solution Approach 1:
The tissue separating members are nested within the cannula in a compact configuration, allowing the complex multi-component device to be delivered through a single insertion point and then deployed sequentially, simplifying the overall insertion process while maintaining functional complexity where needed
Solution Approach 2:
The tissue separating members are designed to be dynamically deployable and retractable, transitioning from a compact stored state within the cannula to an expanded operational state during tissue separation, allowing the device to adapt its complexity based on operational requirements
Data Source
AI summary
Tissue transfer devices suitable for transfer of tissues include a cannula, a plurality of tissue separating members outwardly extendable from the cannula, a tissue reservoir disposed in fluid communication with the cannula and a pump disposed in fluid communication with the tissue reservoir.