Tissue Piece Winding Using Peeling Means
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Solution Overview
Problem
Existing methods for forming tissue pieces for tissue arrays face challenges in achieving stable and accurate winding around a core rod, particularly due to the fusion of embedding media like paraffin with the mounting block, leading to manual and non-automated processes that can damage tissues.
Innovation Solution
A method involving a peeling means with a second embedding medium of lower melting point, applied between the sheet-like tissue piece and the mounting block, allows for stable and accurate winding by preventing fusion and enabling automated processing, along with the use of a mounting block with a heater and a detachable plate for tissue handling and identification.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Ease of operation
If the sheet-like tissue piece is heated on the mounting block to improve flexibility for winding, then the embedding medium softens and flexibility is improved, but the tissue piece is welded to the mounting block by fusion of the embedding medium, preventing automated winding
Solution Approach 1:
A peeling means is introduced as an intermediary layer between the tissue piece and the mounting block. This peeling means prevents direct adhesion while allowing the tissue piece to be easily peeled off after winding, thus enabling automated processing without manual intervention to separate the tissue from the mounting block
Solution Approach 2:
The melting point of the embedding medium is changed by using a second embedding medium with a lower melting point for the peeling means. This parameter change allows the peeling means to be peeled off easily when heated, preventing welding of the tissue piece to the mounting block while maintaining the necessary flexibility for winding
2Reliability
If manual winding is used to prevent tissue destruction, then tissue integrity is maintained, but processing efficiency is reduced and automation is lost
Solution Approach 1:
The peeling means acts as a mediator that enables the tissue piece to be handled without direct contact with the mounting block during winding. This prevents tissue destruction while allowing automated winding mechanisms to be used, thereby maintaining both tissue integrity and processing efficiency
Solution Approach 2:
By changing the physical properties of the peeling means (using a material with lower melting point), the tissue piece can be heated to the appropriate temperature for winding without risk of welding to the mounting block. This enables automated winding while preserving tissue integrity
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
Enables stable, accurate, and automated winding of tissue pieces around the core rod without tissue destruction, facilitating the formation of high-quality tissue arrays with improved handling and identification.
Implementation Method 1
applying a peeling means which easily enables peeling of the tissue piece from the mounting block between the mounting block and the tissue piece
Implementation Method 2
winding the sheet-like tissue piece around the core rod while heating the tissue piece on the mounting block
Data Source
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AI summary
The invention provides a method for forming tissue pieces which allows stable and accurate winding around a core rod in rolling a sheet-like tissue piece, and a device therefor. In the tissue pieces used as each tissue piece in a tissue array obtained by arranging the tissue pieces on a substrate in an array form, the method for forming a roll-shaped tissue piece 6 obtained by rolling a sheet-like tissue piece 8 is characterized by the facts that the sheet-like tissue piece 8 is produced by slicing a tissue block 5 obtained by embedding the tissues with an embedding medium, the sheet-like tissue piece 8 is placed on a mounting block 12, peeling means 13 which easily enables peeling of the tissue piece 8 from the mounting block 12 is applied between the mounting block 12 and the tissue piece 8, and the tissue piece 8 is wound around a core rod 11 while heating the tissue piece 8 on the mounting block 12.