Titanium-Magnesium Implant Structure for Stress Shielding Reduction

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Solution Overview

Problem

Current medical implant alloys, such as titanium and magnesium alloys, face challenges such as 'stress shielding' due to mismatched Young's modulus with natural bone, poor bone-promoting properties, and excessive degradation, leading to inefficiencies in bone repair and replacement, especially in pelvic bone and hip joint applications.

Innovation Solution

A titanium-magnesium interpenetrating phase composite structure is prepared using additive manufacturing and pressureless infiltration or hot isostatic pressing, creating a porous skeleton with a Young's modulus adjustable within the range of 10-20 GPa and compressive strength exceeding 180 MPA, combined with a hydroxyapatite coating to enhance biocompatibility and bone integration.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Strength

If titanium alloy is used for medical implant, then strength is improved, but bone-promoting property deteriorates and bone-forming period is prolonged

Engineering Contradiction:
ImprovestrengthVSAvoidbone-promoting property
Core Design Contradiction:
StrengthVSReliability

Solution Approach 1:

The patent creates a composite structure by filling magnesium alloy powder into the porous titanium alloy skeleton, combining the high strength of titanium with the bone-promoting properties of magnesium. The titanium alloy provides structural support while the magnesium alloy fills the pores to enhance osteogenesis, resolving the contradiction between strength and bone-promoting property.

Inventive Principle:
Principle #40Composite materials

Solution Approach 2:

The patent utilizes a porous titanium alloy skeleton with controlled porosity (30-70%) created through additive manufacturing. This porous structure allows magnesium alloy powder to be filled inside, increasing the surface area for bone attachment and facilitating bone ingrowth, thereby improving bone-promoting property while maintaining overall structural strength.

Inventive Principle:
Principle #31Porous materials

2Reliability

If magnesium alloy is used for medical implant, then bone-promoting activity is improved, but degradation resistance deteriorates

Engineering Contradiction:
Improvebone-promoting activityVSAvoiddegradation resistance
Core Design Contradiction:
ReliabilityVSDuration of action of stationary object

Solution Approach 1:

The patent combines magnesium alloy powder with titanium alloy skeleton to create a composite structure where the titanium provides long-term structural support and corrosion resistance, while the magnesium provides bone-promoting activity. The titanium matrix protects the magnesium from rapid degradation while still allowing it to maintain bone health.

Inventive Principle:
Principle #40Composite materials

Solution Approach 2:

The patent applies different materials to different locations within the implant structure - the titanium alloy forms the external skeleton that provides structural integrity and degradation resistance, while the magnesium alloy is localized within the porous pores to provide bone-promoting activity at the bone-implant interface, where it is most needed.

Inventive Principle:
Principle #3Local quality

3Manufacturing precision

If traditional processing techniques are used for implant preparation, then manufacturing precision is improved, but production cost deteriorates

Engineering Contradiction:
Improvemanufacturing precisionVSAvoidproduction cost
Core Design Contradiction:
Manufacturing precisionVSEase of manufacture

Solution Approach 1:

The patent employs additive manufacturing technology that allows for digital design and direct fabrication of complex porous structures with precise control over porosity (30-70%) and pore distribution. This digital approach enables customization without requiring expensive custom molds or extensive material removal, reducing production costs while maintaining high manufacturing precision.

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The composite structure effectively addresses 'stress shielding' by matching the mechanical properties of natural bone, enhances bone formation through magnesium's bone-promoting activity, and slows down magnesium degradation with the hydroxyapatite coating, thereby improving the efficacy and durability of pelvic bone and hip joint implants.

Implementation Method 1

preparing, based on a selective laser melting technique or a laser powder bed fusion technique, titanium alloy powder into a porous skeleton

Methodology Applied
Scientific EffectSelective laser melting: Laser

Implementation Method 2

filling magnesium after being melted into pores of the porous skeleton

Methodology Applied
Scientific EffectPressureless infiltration: Capillary Action

Implementation Method 3

filling magnesium after being melted into pores of the porous skeleton by means of magnesium pressureless infiltration or hot isostatic pressing

Methodology Applied
Scientific EffectHot isostatic pressing: Hot Isostatic Pressing

Implementation Method 4

covering a surface of the titanium-magnesium interpenetrating phase composite structure with a hydroxyapatite coating

Methodology Applied
Scientific EffectHydroxyapatite coating: Deposition (physical)

Data Source

PatentUS12245944B1Method for preparing a heterogeneous metal composite structure for medical implantation
Publication Date: 2025.03.11 JILIN UNIVERSITY
  • US12245944B1 patent drawing
  • US12245944B1 patent drawing
  • US12245944B1 patent drawing

AI summary

Disclosed is a method for preparing a heterogeneous metal composite structure for medical implantation, including the steps of: step 1, preparing titanium alloy powder into a porous skeleton according to different printing strategies; step 2, filling magnesium after being melted into pores of the porous skeleton; and step 3, cooling a titanium-magnesium interpenetrating phase composite structure prepared in step 2 to room temperature, and covering a surface of the titanium-magnesium interpenetrating phase composite structure with a hydroxyapatite coating. In the present disclosure, a porous lattice dot-array structure of titanium alloy is used as a skeleton, and the skeleton pore is filled by pressureless infiltration of magnesium or hot isostatic pressure.