Titanium Tube for Platelet Rich Fibrin Separation
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Solution Overview
Problem
The use of glass and glazed silicon tubes for obtaining Platelet Rich Fibrin (PRF) can impair the formation of fibrin structures due to silica particles and improper material contact, leading to suboptimal fibrin structure and efficiency in high-speed centrifugation.
Innovation Solution
A tube made from pure titanium or titanium alloys with a concave curve design at the top, eliminating the need for a cap and enhancing centrifuge efficiency, and featuring a lock system for easy removal of PRF without contamination, along with a modified surface for improved platelet aggregation.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Ease of manufacture
If glass or glazed silicon tubes are used for obtaining PRF, then the tubes are easy to manufacture and inexpensive, but the silica particles and improper material contact impair fibrin structure formation and reduce centrifugation efficiency
Solution Approach 1:
The patent changes the material parameter of the tube from glass or glazed silicon to titanium or titanium alloy. This material substitution eliminates silica particle contamination and improves fibrin structure formation during centrifugation, directly resolving the contradiction between ease of manufacture and fibrin structure quality.
Solution Approach 2:
The patent employs titanium or titanium alloy materials for the tube construction. These composite materials provide both mechanical strength and biocompatibility, creating an optimal environment for PRF preparation while avoiding the harmful effects of glass or silicon materials.
2Ease of manufacture
If glass or glazed silicon tubes are used for PRF preparation, then the manufacturing cost is low, but the centrifugation efficiency at high speeds is reduced
Solution Approach 1:
The patent changes the material parameter from glass/silicon to titanium, which has superior mechanical properties and surface characteristics that enhance centrifugation efficiency. The titanium material allows for effective high-speed centrifugation while maintaining reasonable manufacturing costs through optimized design.
3Reliability
If a cap is added to the tube to prevent contamination, then the protection against contamination is improved, but the device complexity and potential fibrin structure impairment increase
Solution Approach 1:
The patent removes the cap component entirely by designing a tube system where the blood sample is processed in an open configuration. The titanium tube material itself provides sufficient protection and control, eliminating the need for additional capping mechanisms and reducing overall device complexity.
Solution Approach 2:
The titanium tube material acts as an intermediary that provides both structural integrity and contamination control without requiring additional components. The material properties of titanium create a controlled environment for blood processing without the need for caps or seals.
4Ease of manufacture
If the tube material contacts blood improperly, then the ease of manufacture is maintained, but the platelet aggregation and fibrin formation are impaired
Solution Approach 1:
The patent changes the material parameter from glass or glazed silicon to titanium or titanium alloy. This material substitution fundamentally alters the surface properties to promote proper platelet aggregation and fibrin formation while maintaining manufacturing feasibility through established titanium fabrication processes.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The titanium tube design results in a more homogeneous and superior fibrin structure, allowing for efficient high-speed centrifugation and easy retrieval of PRF, suitable for various medical and dental applications.
Implementation Method 1
the tube is centrifuged at once in the centrifuge previously adjusted to 2700 RPM for 12 min or 3000 RPM for 10 min. Following the centrifuge procedure, a layer of the red blood cells accumulated at the bottom of the tube, acellular plasma with low thrombocytes at the top of the tube and Platelet Rich Fibrin, that is PRF coagulum comes off in the middle of the tube
Implementation Method 2
Since the platelet activation and fibrin polymerization are triggered immediately in the lack of anticoagulant, the tube is centrifuged at once
Data Source
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AI summary
Invention; It is about the tubes used to obtain blood products through centrifuge in order to cure open and closed injuries, to heal hard and soft tissues and to diagnose in all fields of medicine and dentistry. Platelet Rich Fibrin (PRF) obtained in the tubes the surface of which contacts blood and made from pure titanium or titanium alloys has a better structure of fibrin than that is obtained through classical methods. The efficiency of the high speed centrifuge is increased with this designed tube and Platelet Rich Fibrin can be removed from the tube without spoiling it.