Integrated TMS Coil with Optical Fiber Probes and Liquid Cooling

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Solution Overview

Problem

Conventional Transcranial Magnetic Stimulation (TMS) devices face challenges in detecting therapeutic effects in real-time due to interference between optical fiber probes and the TMS coil, inadequate heat dissipation, and the need for expensive imaging systems, which limits the adjustment of stimulation parameters and reduces therapeutic effectiveness.

Innovation Solution

An integrated TMS coil design featuring optical fiber probes mounted on the coil housing with a silica gel sheet for secure positioning, a cooling liquid circulation system within a hollow copper tube, and a near-infrared brain function imager for real-time effect detection, allowing for simultaneous and independent operation of the detection and treatment regions without interference.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If optical fiber probes are mounted on the TMS coil for real-time detection, then therapeutic effect detection capability is improved, but interference between probes and coil structure occurs

Engineering Contradiction:
Improvetherapeutic effect detectionVSAvoidprobe and coil structure integration
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The device is divided into independent functional modules: the TMS coil assembly and the optical fiber probe assembly are separated but integrated through the coil housing. The probes are mounted on the housing rather than directly on the coil windings, allowing independent optimization of each component while maintaining their functional relationship for simultaneous operation.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The coil housing serves as an intermediary structure that holds both the TMS coil and the optical fiber probes. This mediator component allows the probes and coil to coexist without direct interference, providing mechanical support and spatial organization while enabling their functions to work together harmoniously.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Measurement precision

If conventional expensive imaging systems are used for detection, then measurement accuracy is improved, but device cost and complexity increase

Engineering Contradiction:
Improvebrain function detection accuracyVSAvoiddetection system structure
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

Instead of using complex expensive imaging systems like fMRI or PET, the invention employs near-infrared spectroscopy (NIRS) with optical fiber probes that detect brain function through light absorption and scattering properties. This optical copying method provides sufficient measurement accuracy for brain oxygenation and blood flow changes while being significantly simpler and more cost-effective than conventional imaging systems.

Inventive Principle:
Principle #26Copying

Solution Approach 2:

The optical fiber probe system uses inexpensive optical components and can be easily replaced or reconfigured. The probes are relatively simple in construction compared to expensive imaging systems, allowing for cost-effective real-time monitoring without requiring complex infrastructure or expensive equipment maintenance.

Inventive Principle:
Principle #27Cheap short-living objects (Disposable)

3Power

If TMS coil operates at high power for effective treatment, then therapeutic effect is improved, but heat generation increases

Engineering Contradiction:
ImproveTMS stimulation powerVSAvoidcoil temperature
Core Design Contradiction:
PowerVSTemperature

Solution Approach 1:

The invention incorporates a liquid cooling system where coolant flows through channels in the coil housing or coil structure. This hydraulic cooling method efficiently removes heat generated during high-power TMS operation, allowing the coil to operate at therapeutic power levels without excessive temperature rise that would damage components or discomfort the patient.

Inventive Principle:
Principle #29Pneumatics and hydraulics

4Area of stationary object

If multiple probes are arranged on the coil housing, then detection coverage is improved, but probe positioning and stability become difficult

Engineering Contradiction:
Improvedetection coverage areaVSAvoidprobe positioning accuracy
Core Design Contradiction:
Area of stationary objectVSManufacturing precision

Solution Approach 1:

The coil housing is designed with asymmetric or specifically positioned mounting locations for optical fiber probes that correspond to the anatomical layout of the brain regions being monitored. Rather than symmetric distribution, the probe positions are strategically placed to cover critical brain areas, with each probe location optimized for its specific detection function while maintaining stable mechanical mounting.

Inventive Principle:
Principle #4Asymmetry

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Enables real-time detection of therapeutic effects, adjusts stimulation parameters for optimal outcomes, improves heat dissipation, and reduces the device's volume while maintaining effective treatment and testing accuracy.

Implementation Method 1

TMS uses a pulsed transient magnetic field to pass through the skull without hindrance and pain, and induces currents in the skull to stimulate the cerebral cortical nerves

Methodology Applied
Scientific EffectElectromagnetic induction: Electromagnetic Induction

Implementation Method 2

a cooling liquid circulation system within a hollow copper tube

Methodology Applied
Scientific EffectConvection cooling: Convection

Implementation Method 3

A miniature near-infrared brain function testing device uses a processor to respectively set the transmitting and receiving frequencies of near-infrared rays having wavelengths of 690 nm and 830 nm

Methodology Applied
Scientific EffectNear-infrared spectroscopy: Absorption Spectroscopy

Data Source

PatentUS12097381B2Integrated TMS coil for brain testing and treatment
Publication Date: 2024.09.24 WUHAN YIRUIDE MEDICAL EQUIPMENT NEW TECHNOLOGY CO LTD
  • US12097381B2 patent drawing
  • US12097381B2 patent drawing
  • US12097381B2 patent drawing

AI summary

An integrated Transcranial Magnetic Stimulation (TMS) coil for brain function testing and treatment is provided. The coil includes a coil housing. A figure-eight coil is provided inside the coil housing, and the coil housing is provided with two waist-like bosses for limiting a position of the coil, eight mounting holes are formed on the coil housing, and an optical fiber holder is provided in each of the mounting holes for mounting an optical fiber probe, a silica gel sheet is provided inside the coil housing for limiting movement of the optical fiber holders, a lead-out of the coil passes through the bottom of the coil housing and is connected to a TMS instrument, and a signal end of the optical fiber probe is connected to a near-infrared brain function imager.