Tobacco-Derived Pyrazines from Biomass Conversion

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Solution Overview

Problem

There is a desire to utilize waste components from the Nicotiana species, such as tobacco, to create additional products beyond traditional smoking and smokeless tobacco items, aiming to develop products entirely derived from this plant source.

Innovation Solution

Methods are developed to form pyrazines from tobacco-derived carbon and nitrogen sources, involving the use of tobacco cellulosic sugars and proteins, where the process includes delignification, hydrolysis, and enzymatic treatment to produce pyrazines, which can be incorporated into tobacco products like cigarettes or snus.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Adaptability or versatility

If tobacco biomass is utilized only for traditional smoking and smokeless tobacco products, then the use of tobacco waste is limited, but the ability to create additional products from tobacco waste is constrained

Engineering Contradiction:
Improveproduct diversity from tobaccoVSAvoidprocessing complexity
Core Design Contradiction:
Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The tobacco plant is divided into different components (leaves, stems, roots) that can be processed separately into different products. The processing method segments the biomass into carbon sources, nitrogen sources, and other components that can be independently utilized to create various flavorants and chemical products beyond traditional tobacco items.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent applies parameter changes by transforming tobacco biomass through controlled chemical and enzymatic processes at specific temperatures and pH levels. The method uses enzymatic hydrolysis at controlled temperatures to convert biomass components into usable chemical building blocks, enabling the creation of diverse products from the same raw material.

Inventive Principle:
Principle #35Parameter changes

2Quantity of substance

If tobacco waste is converted into pyrazines through enzymatic hydrolysis and chemical reactions, then additional valuable products are created, but the processing steps and chemical reactions increase complexity

Engineering Contradiction:
Improvepyrazine yieldVSAvoidprocessing steps
Core Design Contradiction:
Quantity of substanceVSDevice complexity

Solution Approach 1:

The patent performs preliminary enzymatic hydrolysis of tobacco biomass to break down complex carbohydrates and proteins into simpler sugar and amino acid building blocks before the main chemical reaction. This preliminary action prepares the biomass components for efficient conversion into pyrazines, reducing the complexity of subsequent processing steps.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The method uses water as an intermediary medium to facilitate the enzymatic hydrolysis and subsequent chemical reactions. The aqueous environment serves as a mediator that enables efficient interaction between enzymes, substrates, and reaction conditions, simplifying the overall processing system while maintaining high pyrazine yield.

Inventive Principle:
Principle #24Intermediary (Mediator)

3Adaptability or versatility

If traditional tobacco products are used, then the flavor and aroma are established, but the ability to enhance flavor using alternative sources is limited

Engineering Contradiction:
Improveflavor enhancement capabilityVSAvoidtobacco waste utilization
Core Design Contradiction:
Adaptability or versatilityVSLoss of substance

Solution Approach 1:

The patent converts tobacco waste, which would otherwise be discarded, into valuable flavorant compounds through enzymatic and chemical processing. The waste biomass is transformed into pyrazines and other flavor-enhancing chemicals that can be used to enhance tobacco products, turning a harmful waste stream into a beneficial resource.

Inventive Principle:
Principle #22Blessing in disguise (Convert harm into benefit)

Solution Approach 2:

The method uses the tobacco plant's own components (carbohydrates, proteins, amino acids) as the raw materials for creating flavorants. The biomass essentially serves itself by being converted into valuable chemical products through its inherent components, eliminating the need for external additives and maximizing the utilization of tobacco waste.

Inventive Principle:
Principle #25Self-service

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The method effectively converts tobacco biomass into valuable pyrazines that can enhance the flavor and aroma of tobacco products, providing a new use for waste tobacco materials and potentially improving product quality.

Implementation Method 1

heating the reactant solution to a reactant temperature and holding the reactant solution at the reactant temperature for a time sufficient to produce a reactant product comprising at least one tobacco-derived pyrazine

Methodology Applied
Scientific EffectThermal reaction: Heating

Implementation Method 2

The step of isolating the at least one tobacco-derived pyrazine from the reactant product can comprise at least one of liquid-liquid extraction of the reactant product

Methodology Applied
Scientific EffectLiquid-liquid extraction: Liquid-Liquid Extraction

Implementation Method 3

The step of isolating the at least one tobacco-derived pyrazine from the reactant product can comprise at least one of liquid-liquid extraction of the reactant product, liquid-solid extraction of the reactant product, and simple distillation of the reactant product

Methodology Applied
Scientific EffectDistillation: Distillation

Data Source

PatentUS10499684B2Tobacco-derived flavorants
Publication Date: 2019.12.10 R J REYNOLDS TOBACCO COMPANY
  • US10499684B2 patent drawing
  • US10499684B2 patent drawing
  • US10499684B2 patent drawing

AI summary

Methods of forming pyrazines from reactants derived from a plant of the Nicotiana species, including receiving an aqueous reactant solution including at least one tobacco-derived cellulosic sugar and at least one tobacco-derived amino acid, heating the reactant solution to a reactant temperature and holding the reactant solution at the reactant temperature for a reactant time to produce a reactant product including at least one tobacco-derived pyrazine, and isolating the at least one tobacco-derived pyrazine from the reactant product. Tobacco products incorporating the tobacco-derived pyrazines are also provided.