Segmented Light Guide Multiplexing for TOF PET Depth Encoding

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Solution Overview

Problem

Existing PET systems face challenges in achieving high spatial resolution due to increased data size and computational inefficiency, particularly with depth-encoding and time-of-flight readouts, which exacerbate the need for efficient signal multiplexing while maintaining depth-of-interaction and time resolution.

Innovation Solution

A particle detection system utilizing a segmented light guide with prismatoid segments for deterministic light sharing, allowing multiplexing of optical sensors and anodes/cathodes for energy and timestamp readouts, respectively, coupled with a processor to determine primary interaction and depth-of-interaction using machine learning.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If n-to-1 scintillator modules-to-readout pixel coupling is used to improve spatial resolution, then spatial resolution is improved, but data size increases exponentially

Engineering Contradiction:
Improvespatial resolutionVSAvoiddata size
Core Design Contradiction:
Measurement precisionVSQuantity of substance

Solution Approach 1:

The light guide is segmented into multiple sections, each coupled to a subset of optical sensors. This segmentation allows the system to process light signals from multiple scintillator modules through shared optical sensors, reducing the total number of readout channels needed while maintaining spatial resolution capabilities.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

Each optical sensor is designed to receive light signals from multiple scintillator modules simultaneously through the segmented light guide structure. This multi-functionality allows a single optical sensor to serve multiple detection purposes, reducing the overall number of sensors and connections required in the system.

Inventive Principle:
Principle #6Universality (Multi-functionality)

2Measurement precision

If depth-encoding is implemented to mitigate parallax error, then spatial resolution uniformity is improved, but the number of LORs increases exponentially

Engineering Contradiction:
Improvespatial resolution uniformityVSAvoidnumber of LORs
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The light guide is divided into multiple depth-encoded segments along the axial direction. Each segment corresponds to a specific depth range, allowing the system to determine depth of interaction by identifying which segment detects the light signal. This segmentation provides depth encoding capability without requiring exponential increase in LORs.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

Depth encoding is achieved by adding the axial dimension to the light guide structure, creating segmented sections along the depth direction. This dimensional approach allows depth information to be extracted from the spatial distribution of light signals across segments, avoiding the need for exponential LOR multiplication.

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

3Device complexity

If multiplexing of optical sensors is used to reduce data size, then computational complexity is reduced, but timing resolution may be impacted

Engineering Contradiction:
Improvecomputational complexityVSAvoidtiming resolution
Core Design Contradiction:
Device complexityVSMeasurement precision

Solution Approach 1:

The light guide is segmented into multiple sections that are coupled to different subsets of optical sensors. This segmentation ensures that timing-critical signals are routed to dedicated sensors with minimal multiplexing, while less time-sensitive energy information can be multiplexed. The segmented structure allows differential handling of timing and energy channels.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

Different regions of the light guide are optimized for different functions: segments coupled to timing-sensitive optical sensors are designed for fast signal transmission, while other segments can be optimized for energy measurement with more aggressive multiplexing. This local optimization maintains timing resolution where needed while reducing computational complexity elsewhere.

Inventive Principle:
Principle #3Local quality

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The system achieves improved energy and depth-of-interaction resolution with retained high timing resolution and reduced computational complexity, enabling efficient data processing and accurate event detection.

Implementation Method 1

Each prismatoid segment may be configured to redirect particles between scintillator modules in contact with the respective prismatoid segment

Methodology Applied
Scientific EffectLight redirection: Refraction

Implementation Method 2

The scintillator array may comprise a second plurality of scintillator modules

Methodology Applied
Scientific EffectScintillation: Scintillation

Data Source

PatentUS20250383462A1System and method for power-efficient multiplexing for high resolution time-of-flight positron emission tomography modules with intercrystal light sharing
Publication Date: 2025.12.18 THE RES FOUNDATION FOR THE STATE UNIV OF NEW YORK
  • US20250383462A1 patent drawing
  • US20250383462A1 patent drawing
  • US20250383462A1 patent drawing

AI summary

A multiplexing scheme for both energy and timing information is provided for a particle detection system having an optical sensor array with multiple optical sensors. Each optical sensor is associated with multiple scintillator modules. The system has a segmented prismatoid light guide comprising multiple prismatoid segments. Each segment is associated with multiple optical sensors, where the optical sensors are adjacent. One end each scintillator module is in contact with its associated optical sensor and the other is in contact with its associated segment. Multiple optical sensors may be connected to an energy readout channel, respectively, such that optical sensors associated with the same segments are not connected to the same energy readout channel. Each energy readout channel has at least two timestamps associated therewith.