Tomato Hybrid Breeding Segmentation for Genetic Uniformity

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Solution Overview

Problem

Current plant breeding methods face challenges in developing uniform tomato varieties with desirable traits such as yield, disease resistance, and environmental stress tolerance, as they often result in unpredictable performance due to genetic non-uniformity in hybrid plants.

Innovation Solution

The development of tomato hybrid SVTM9030, tomato line PSQ-9Z15-3849V, and tomato line PSQ-9Z19-9229, which involve creating homozygous inbred plants, crossing them to produce hybrid plants with specific genetic loci conferring traits like herbicide tolerance, insect resistance, and modified carbohydrate metabolism through genetic engineering techniques such as genome editing with engineered nucleases.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Adaptability or versatility

If conventional breeding methods are used to develop tomato varieties, then genetic diversity is achieved, but uniformity and predictability of performance deteriorate

Engineering Contradiction:
Improvegenetic diversityVSAvoiduniformity of plants
Core Design Contradiction:
Adaptability or versatilityVSManufacturing precision

Solution Approach 1:

The breeding process is segmented into distinct phases: developing homozygous inbred lines through multiple generations of selfing, then crossing these standardized lines to produce uniform F1 hybrids. This segmentation allows genetic diversity to be captured in the inbred lines while ensuring uniformity in the commercial hybrid plants.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The genetic uniformity parameter is changed by transitioning from outcrossing to self-pollination over multiple generations, achieving homozygosity. This parameter change enables the production of uniform F1 hybrids with predictable performance while maintaining the ability to incorporate diverse genetic traits.

Inventive Principle:
Principle #35Parameter changes

2Manufacturing precision

If multiple generations of selfing are performed to create homozygous lines, then uniformity of plants is improved, but time required for breeding increases

Engineering Contradiction:
Improveuniformity of plantsVSAvoidbreeding cycle duration
Core Design Contradiction:
Manufacturing precisionVSLoss of time

Solution Approach 1:

Homozygous inbred lines are developed in advance through multiple generations of selfing before the actual hybridization program begins. These pre-developed lines serve as standardized parental stocks that can be repeatedly crossed to produce uniform F1 hybrids without requiring additional selfing generations for each cross.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

Once homozygous inbred lines are established, they serve as reusable genetic templates. The same parental lines can be crossed repeatedly to produce genetically identical F1 hybrids, eliminating the need to re-develop uniformity from scratch for each breeding cycle.

Inventive Principle:
Principle #26Copying

3Manufacturing precision

If homozygous inbred plants are crossed to produce F1 hybrids, then uniformity and predictability are improved, but genetic diversity in the hybrid population decreases

Engineering Contradiction:
Improveuniformity of hybrid plantsVSAvoidgenetic diversity in hybrid population
Core Design Contradiction:
Manufacturing precisionVSAdaptability or versatility

Solution Approach 1:

Genetic diversity is segmented and captured within the homozygous parental lines through extensive breeding and selection. The F1 hybrid population then uniformly expresses the combined genetics of these diverse parents, achieving uniformity without sacrificing the underlying genetic diversity encoded in the parental genomes.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The F1 hybrid combines genetic material from two genetically diverse homozygous parents into a uniform composite population. This composite structure maintains the genetic diversity benefits of both parents while producing a uniform hybrid population with consistent performance characteristics.

Inventive Principle:
Principle #40Composite materials

Data Source

PatentUS12127526B2Tomato line PSQ-9Z19-9229
Publication Date: 2024.10.29 SEMINIS VEGETABLE SEEDS INC

AI summary

The invention provides seeds and plants of tomato line PSQ-9Z19-9229. The invention thus relates to the plants, seeds, plant parts, and tissue cultures of tomato line PSQ-9Z19-9229 and to methods for producing a tomato plant produced by crossing such plants with themselves or with another plant, such as a tomato plant of another genotype. The invention further relates to seeds and plants produced by such crossing. The invention further relates to plants, seeds, plant parts, and tissue cultures of tomato line PSQ-9Z19-9229 comprising introduced beneficial or desirable traits.