Tomographic Image Reconstruction Using Compressed Sensing

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Solution Overview

Problem

Conventional image reconstruction methods for tomographic images, especially in emission and transmission tomography, face challenges with Poisson noise, requiring numerous measurements and high patient doses, which limits the efficiency and accuracy of image reconstruction.

Innovation Solution

An image reconstruction method using a non-analytical algorithm that minimizes a functional incorporating a system matrix based on geometric or physical contributions of voxels to detector data, along with a sparse representation in an orthogonal basis, effectively addressing Poisson noise and enabling reconstruction from fewer measurements.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If conventional image reconstruction methods are used for tomographic images with Poisson noise, then measurement precision can be maintained, but the number of measurements required increases and patient dose increases

Engineering Contradiction:
Improveimage reconstruction accuracyVSAvoidnumber of measurements and patient dose
Core Design Contradiction:
Measurement precisionVSQuantity of substance

Solution Approach 1:

The patent transforms the Poisson noise model into a Gaussian noise model through variance stabilization transformation, enabling the application of Compressed Sensing techniques. This parameter transformation allows reconstruction from fewer measurements while maintaining accuracy by changing the statistical characteristics of the noise from Poisson to Gaussian distribution

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent replaces the conventional analytical reconstruction approach with an iterative optimization-based Compressed Sensing method. This substitution enables accurate reconstruction from undersampled data by solving an optimization problem that incorporates sparsity constraints and transformed noise statistics

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

2Productivity

If the number of measurements is reduced to decrease patient dose and acquisition time, then productivity improves, but measurement precision deteriorates due to Poisson noise

Engineering Contradiction:
Improveacquisition time and patient dose efficiencyVSAvoidimage reconstruction accuracy
Core Design Contradiction:
ProductivityVSMeasurement precision

Solution Approach 1:

The patent applies variance stabilization transformation to change the noise parameter from Poisson (variance equals mean) to Gaussian (constant variance), enabling effective noise handling with fewer measurements and thus improving productivity without sacrificing precision

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent performs preprocessing of the detector data through variance stabilization transformation before reconstruction. This preliminary action prepares the data by transforming the noise characteristics, making it suitable for Compressed Sensing reconstruction with reduced measurements

Inventive Principle:
Principle #10Preliminary action

Data Source

PatentEP2387779B1Tomographic imaging using poissonian detector data
Publication Date: 2020.05.06 HELMHOLTZ ZENT MUENCHEN DEUT FORSCHUNGSZENTRUM FUER GESUNDHEIT & UMWELT (GMBH)
  • EP2387779B1 patent drawingFigure 1
  • EP2387779B1 patent drawingFigure 2
  • EP2387779B1 patent drawingFigure 3A~3D

AI summary

An image reconstruction method for reconstructing a tomographic image (f j ) of a region of investigation within an object (1), comprises the steps of providing detector data (y i ) comprising Poisson random values measured at an i-th of a plurality of different positions, e.g. i = (k,l) with pixel index k on a detector device and angular index l referring to both the angular position (a l ) and the rotation radius (r l ) of the detector device (10) relative to the object (1), providing a predetermined system matrix A ij assigning a j-th voxel of the object (1) to the i-th detector data (y i ), and reconstructing the tomographic image (f j ) based on the detector data (y i ), said reconstructing step including a procedure of minimizing a functional F(f) depending on the detector data (y i ) and the system matrix A ij and additionally including a sparse or compressive representation of the object (1) in an orthobasis T, wherein the tomographic image (f j ) represents the global minimum of the functional F(f). Furthermore, an imaging method and an imaging device using the image reconstruction method are described.