Toothpaste Composition with Layered Silicate Clays for Fluoride Stability

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Solution Overview

Problem

Existing toothpaste compositions face challenges in delivering high levels of fluoride due to deactivation by other ingredients, particularly abrasive components, which affects the remineralization of teeth and the balance between demineralization and remineralization processes.

Innovation Solution

A toothpaste composition incorporating silica or calcium-based abrasives, 1:1 layered silicate clay, and 2:1 layered silicate clay, which enhances fluoride availability and stability, ensuring maximum fluoride delivery and resistance to degradation during storage.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If fluoride source is incorporated in toothpaste composition, then remineralisation of tooth is enhanced, but fluoride ions are deactivated by abrasive components reducing availability

Engineering Contradiction:
Improveremineralisation effectivenessVSAvoidfluoride ion availability
Core Design Contradiction:
ReliabilityVSQuantity of substance

Solution Approach 1:

The patent introduces 1:1 layered silicate clay and 2:1 layered silicate clay as intermediary substances that mediate between the fluoride source and abrasive components. These clays act as protective intermediaries that prevent direct deactivation of fluoride ions by calcium-containing abrasives, while still allowing fluoride to be delivered to the tooth enamel for remineralisation.

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The patent creates a composite toothpaste formulation that combines fluoride source, abrasive components (including calcium-containing abrasives), and layered silicate clays. This composite structure allows the different components to work together synergistically, where the clays protect the fluoride while the abrasives provide cleaning action, resolving the contradiction between maintaining fluoride availability and using effective abrasives.

Inventive Principle:
Principle #40Composite materials

2Ease of manufacture

If calcium-containing abrasives are used for polishing enamel, then polishing performance is improved, but fluoride compatibility is reduced due to deactivation

Engineering Contradiction:
Improvepolishing performanceVSAvoidfluoride compatibility
Core Design Contradiction:
Ease of manufactureVSReliability

Solution Approach 1:

The layered silicate clays serve as intermediary substances between calcium-containing abrasives and fluoride source. These clays physically separate or chemically buffer the interaction between calcium ions from abrasives and fluoride ions, preventing deactivation while allowing both components to perform their respective functions - abrasives for polishing and fluoride for remineralisation.

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The patent changes the chemical environment parameters by introducing layered silicate clays that alter the availability and reactivity of calcium ions. This parameter change allows calcium-containing abrasives to maintain their polishing effectiveness while reducing their harmful deactivation effect on fluoride, thus improving fluoride compatibility.

Inventive Principle:
Principle #35Parameter changes

3Reliability

If non-calcium-containing abrasives are used to protect fluoride, then fluoride compatibility is improved, but polishing ability is inferior

Engineering Contradiction:
Improvefluoride compatibilityVSAvoidpolishing ability
Core Design Contradiction:
ReliabilityVSEase of manufacture

Solution Approach 1:

The patent merges calcium-containing abrasives (for superior polishing) with layered silicate clays (for fluoride protection) in a single formulation. This combination allows the system to achieve both high polishing ability from calcium abrasives and high fluoride compatibility from the protective clays, overcoming the limitation of using non-calcium abrasives alone.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The patent creates a composite abrasive system that includes both calcium-containing abrasives and layered silicate clays. This composite material approach allows the calcium abrasives to provide excellent polishing performance while the clays simultaneously protect fluoride from deactivation, achieving both high polishing ability and high fluoride compatibility together.

Inventive Principle:
Principle #40Composite materials

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The composition achieves improved remineralization of teeth with increased fluoride availability and resistance to degradation, effectively promoting tooth health by balancing demineralization and remineralization processes.

Implementation Method 1

Fluoride helps in slowing down the demineralisation by interacting with hydroxyapatite to form a stronger compound that is less-susceptible to acid attack. Fluoride ions partially fluoridate hydroxyapatite and simultaneously repair the lattice irregularities and improves remineralisation process.

Methodology Applied
Scientific EffectChemical interaction between fluoride and hydroxyapatite: Chemical Bonding

Implementation Method 2

A toothpaste composition incorporating silica or calcium-based abrasives, 1:1 layered silicate clay, and 2:1 layered silicate clay, which enhances fluoride availability and stability, ensuring maximum fluoride delivery and resistance to degradation during storage.

Methodology Applied
Scientific EffectAdsorption: Adsorption

Implementation Method 3

a toothpaste composition having an abrasive, a source of fluoride, a 2:1 layered silicate clay and a 1:1 layered silicate clay wherein the abrasive is an abrasive silica or a calcium based abrasive

Methodology Applied
Scientific EffectAbrasion: Abrasion

Data Source

PatentEP3393426B1Toothpaste composition
Publication Date: 2020.02.19 UNILEVER NV
  • EP3393426B1 patent drawing

AI summary

The present invention relates to a toothpaste composition, it particularly relates to a toothpaste composition having a fluoride source for enhancing remineralisation of tooth. It is desired that the performance of the fluoride source in a toothpaste composition is improved and in that the fluoride source delivers maximum benefit to tooth without compromising on the other benefits derivable from the toothpaste composition. Accordingly, an object of the present invention is to provide a toothpaste composition which retains a desirable level of soluble fluoride upon storage. It has been surprisingly found by the present inventors that a toothpaste composition having a fluoride source provides for improved remineralisation of the teeth when the composition includes an abrasive silica or a calcium based abrasive, a 1:1 layered silicate clay and a 2:1 layered silicate clay.