Tortuous Artery Flow Profile Reconstruction with Triplex Ultrasound
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Solution Overview
Problem
Existing methods for determining blood flow in arteries using ultrasound assume axial symmetry and do not account for tortuosity, leading to inaccuracies in flow profile determination, especially in arteries with increased tortuosity.
Innovation Solution
A computer-implemented method using triplex ultrasound mode data (B-mode, pulsed wave Doppler, and color/power Doppler) to determine artery dimensions, velocity, and flow asymmetry, allowing reconstruction of the flow profile with analytical expressions, including determination of local artery curvature.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Ease of operation
If axial symmetry assumption is used for flow profile determination, then measurement simplicity is improved, but measurement precision deteriorates in tortuous arteries
Solution Approach 1:
The patent applies asymmetry by introducing a Dean number parameter that quantifies flow asymmetry in curved arteries. Instead of assuming axial symmetry, the method calculates the Dean number based on artery curvature and uses it to determine an asymmetry factor that modifies the flow profile calculation, thereby accurately representing asymmetric flow patterns in tortuous arteries while maintaining measurement simplicity through automated computational processing.
2Device complexity
If traditional Doppler measurements are used, then device complexity is reduced, but measurement precision deteriorates due to inability to capture tortuosity effects
Solution Approach 1:
The patent introduces the Dean number as a new dimensionless parameter that characterizes flow asymmetry in curved arteries. By calculating the Dean number from readily available ultrasound measurements (artery diameter, curvature radius) and using it to determine an asymmetry factor, the method enhances measurement precision without requiring complex additional imaging equipment, thus maintaining device simplicity while improving accuracy.
3Ease of operation
If maximum velocity is assumed to be at artery center, then ease of operation is improved, but measurement precision deteriorates in curved arteries
Solution Approach 1:
The patent addresses the misconception that maximum velocity occurs at the artery center in curved vessels by introducing the Dean number-based asymmetry factor. This factor quantifies the shift in maximum velocity location from the centerline toward the outer wall in curved arteries, allowing the system to automatically correct velocity measurements and maintain operational simplicity while improving velocity location accuracy.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
Enables accurate reconstruction of the flow profile in arteries with tortuosity, improving methods for plaque removal and stent placements by providing precise flow information.
Implementation Method 1
receiving ultrasound imaging data of an artery in triplex mode
Implementation Method 2
pulsed wave Doppler ultrasound data, and color or power Doppler ultrasound data
Data Source
AI summary
The invention relates to determining a flow profile in an artery from ultrasound imaging data. For this end, a computer-implemented method (300) is provided for determining (330) a flow profile based on an artery dimension, a velocity in the artery and a measure of asymmetry, wherein the artery dimension, the velocity in the artery and the measure of asymmetry are determined (320) from ultrasound imaging data comprising B-mode, pulsed wave Doppler, and color or power Doppler ultrasound imaging data.


