Transcutaneous Glucose Sensor with Directional Rate Display

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Solution Overview

Problem

Conventional self-monitoring blood glucose methods for diabetes patients are uncomfortable and infrequent, leading to delayed detection of hyperglycemic or hypoglycemic conditions, which can result in dangerous side effects due to the lack of continuous monitoring and timely insulin therapy decisions.

Innovation Solution

A system comprising a continuous glucose sensor and a receiver that displays a graphical representation of glucose concentration, with a directional arrow indicating the direction and rate of change of the glucose level, and provides alarms for threshold violations, allowing for real-time monitoring and timely interventions.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If conventional self-monitoring blood glucose methods are used, then the monitoring process is simple, but the monitoring frequency is low and detection is delayed

Engineering Contradiction:
Improvemonitoring frequencyVSAvoiddetection delay
Core Design Contradiction:
ProductivityVSLoss of time

Solution Approach 1:

The patent implements continuous glucose monitoring through a transcutaneous sensor that continuously measures interstitial fluid glucose levels, replacing the conventional intermittent finger-prick method. The sensor provides uninterrupted glucose concentration data, enabling real-time detection of glycemic changes and eliminating detection delays associated with infrequent manual testing.

Inventive Principle:
Principle #20Continuity of useful action

2Ease of operation

If conventional finger-prick monitoring is used, then the device complexity is low, but the user comfort and convenience are poor

Engineering Contradiction:
Improveuser comfortVSAvoidsystem complexity
Core Design Contradiction:
Ease of operationVSDevice complexity

Solution Approach 1:

The patent introduces an intermediary transcutaneous sensor system that measures glucose in interstitial fluid rather than requiring direct blood sampling. This intermediary approach uses a sensor probe inserted into the dermis layer, connected to a receiver that processes and displays glucose data, providing a more comfortable alternative to repeated finger pricks while managing system complexity through integrated electronics and data processing.

Inventive Principle:
Principle #24Intermediary (Mediator)

3Reliability

If continuous glucose monitoring is implemented, then real-time detection is achieved, but the device complexity increases

Engineering Contradiction:
Improvedetection accuracyVSAvoidsystem complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent divides the continuous glucose monitoring system into distinct functional segments: a sensor probe for interstitial fluid measurement, a receiver for data processing and display, and an optional alarm system for threshold notifications. This segmentation allows each component to perform its specific function efficiently, improving detection reliability while managing overall system complexity through modular architecture.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent implements feedback mechanisms where the receiver continuously receives glucose concentration data from the sensor, processes the information, and provides real-time visual display and alarm notifications when glucose levels exceed predetermined thresholds. This feedback loop enables timely detection and response to glycemic changes, enhancing detection accuracy and reliability.

Inventive Principle:
Principle #23Feedback

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Enables continuous and comfortable glucose monitoring, allowing for timely interventions and informed insulin therapy decisions, reducing the risk of dangerous glycemic events.

Implementation Method 1

a continuous glucose sensor configured to produce a signal indicative of a glucose concentration in a host

Methodology Applied
Scientific EffectElectrochemical detection:

Data Source

PatentUS8845536B2Transcutaneous analyte sensor
Publication Date: 2014.09.30 DEXCOM INC
  • US8845536B2 patent drawing
  • US8845536B2 patent drawing
  • US8845536B2 patent drawing

AI summary

The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.