Transdermal Drug Interface with Conical Projections

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Solution Overview

Problem

Existing transdermal drug administration devices face challenges in reliably piercing the skin and evenly distributing drugs due to flat microblades that deflect and uneven drug supply through needle paths with lattice patterns.

Innovation Solution

A transdermal drug administration device featuring a flat plate with two-dimensionally arranged conical or pyramidal projections and corresponding openings, where the openings are arranged in proximity to the projections, allowing for even drug delivery and reliable skin piercing.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Device complexity

If flat microblades are used for skin piercing, then the device structure is simple, but the microblades deflect by the skin and fail to perform reliable piercing treatment

Engineering Contradiction:
Improvedevice structureVSAvoidpiercing treatment reliability
Core Design Contradiction:
Device complexityVSReliability

Solution Approach 1:

The patent applies curvature by transforming the flat microblade structure into a three-dimensional conical or pyramidal projection structure. This curved/geometric shape provides structural integrity and prevents deflection during skin piercing, while maintaining manufacturing simplicity through molding processes.

Inventive Principle:
Principle #14Spheroidality (Curvature)

2Device complexity

If a lattice pattern is used for drug-guiding paths, then the device structure is simplified, but drug supply becomes uneven due to surface roughness variations

Engineering Contradiction:
Improvedevice structureVSAvoiddrug supply uniformity
Core Design Contradiction:
Device complexityVSManufacturing precision

Solution Approach 1:

The patent segments the drug delivery system by providing individual openings for each projection, with each opening independently positioned in proximity to its corresponding projection. This segmentation ensures that drug supply to each projection is independent and uniform, eliminating the uneven distribution caused by lattice pattern surface roughness.

Inventive Principle:
Principle #1Segmentation

3Manufacturing precision

If openings are arranged in correspondence with projections, then even drug supply is achieved, but the device requires precise positioning and manufacturing

Engineering Contradiction:
Improvedrug supply uniformityVSAvoidpositioning precision
Core Design Contradiction:
Manufacturing precisionVSEase of manufacture

Solution Approach 1:

The patent merges the opening formation process with the projection formation process, creating both features simultaneously in a single molding operation. This integration eliminates the need for separate positioning and machining steps, achieving precise opening-projection correspondence while simplifying manufacturing.

Inventive Principle:
Principle #5Merging (Combining)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The device ensures almost even drug supply from multiple projections through the skin, preventing deflection and ensuring consistent drug distribution across the skin surface.

Implementation Method 1

a flat plate comprising a plurality of two-dimensionally arranged conical or pyramidal projections capable of piercing the skin

Methodology Applied
Scientific EffectMechanical Force: Mechanical Force

Implementation Method 2

a plurality of openings capable of delivering a drug which are respectively arranged in correspondence with the projections

Methodology Applied
Scientific EffectDiffusion: Diffusion

Data Source

PatentUS7914813B2Interface for transdermal drug administration device
Publication Date: 2011.03.29 HISAMITSU PHARM CO INC
  • US7914813B2 patent drawing
  • US7914813B2 patent drawing
  • US7914813B2 patent drawing

AI summary

It is intended to provide an interface for a transdermal drug administration device that can supply a drug almost evenly and favorably from a plurality of projections through skin. This interface for a transdermal drug administration device has a flat plate 8. The flat plate 8 comprises a plurality of two-dimensionally arranged conical or pyramidal projections 6 capable of piercing skin and a plurality of openings 7 capable of delivering a drug which are respectively arranged in correspondence with the projections. The openings 7 are respectively arranged in proximity to their corresponding projections 6. The flat plate 8 can be made of a metal or ceramics. The ratio between the number of the openings and the number of the projections can be 1:1 to 1:2.