Transdermal Magnesium Delivery via Alkaline Compound and Permeation Enhancers
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Solution Overview
Problem
There is a need for easy-to-use, non-oral products that can effectively deliver magnesium to individuals with magnesium deficiency, as dietary intake is often insufficient and existing methods like Epsom baths or magnesium chloride sprays are impractical or cause skin irritation.
Innovation Solution
A transdermal delivery system using a roll-on, stick, spray, gel, or cream that administers an alkaline magnesium compound to the underarm skin, optimizing absorption through the use of magnesium hydroxide, magnesium sulfate, or magnesium chloride, combined with propanediol and glycerin, to provide a therapeutic dose of elemental magnesium.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Quantity of substance
If magnesium chloride sprays are used for transdermal magnesium delivery, then magnesium can be delivered to the skin, but itching and burning occur on the skin
Solution Approach 1:
The patent changes the concentration parameters of magnesium compounds and modifies the chemical composition by adding soothing ingredients like aloe vera, glycerin, and vitamin E. This adjusts the formulation parameters to reduce skin irritation while maintaining magnesium delivery effectiveness.
Solution Approach 2:
The patent creates a composite transdermal formulation combining multiple magnesium compounds (magnesium chloride, magnesium sulfate, magnesium hydroxide) with skin-conditioning ingredients. This composite approach delivers magnesium while the additional components mitigate skin irritation effects.
2Quantity of substance
If Epsom salts bathing is used for magnesium absorption, then the body can receive magnesium, but the process is time-consuming and impractical
Solution Approach 1:
The patent extracts the essential magnesium delivery function from the time-consuming Epsom bath process and concentrates it into a portable spray formulation. This allows magnesium delivery without requiring full immersion bathing, significantly reducing time commitment.
Solution Approach 2:
The patent replaces the mechanical process of bathing (immersion in water) with a spray application system. This substitution transforms the delivery mechanism from requiring full-body immersion to a quick topical application, eliminating the time-consuming nature of traditional Epsom baths.
3Quantity of substance
If oral magnesium supplements are taken, then magnesium deficiency can be addressed, but unpleasant laxative effects occur
Solution Approach 1:
The patent uses the skin as an intermediary delivery route instead of the gastrointestinal tract. By delivering magnesium transdermally through spray application, the bypasses the digestive system and avoids the laxative effects associated with oral magnesium supplementation.
4Ease of operation
If a transdermal magnesium delivery system is developed, then easy-to-use non-oral product is provided, but skin absorption efficiency must be optimized
Solution Approach 1:
The patent creates a multi-functional spray formulation that simultaneously delivers multiple magnesium compounds (chloride, sulfate, hydroxide) and includes skin-conditioning ingredients. This universal formulation addresses both usability and absorption efficiency by providing comprehensive magnesium delivery through a single convenient application.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
This system allows for efficient and pain-free magnesium absorption, addressing magnesium deficiency while avoiding common issues with oral intake and skin irritation, and can be used in various applications including healthcare, wellness, and athletic recovery.
Implementation Method 1
The process of the alkaline magnesium compound reacting with moisture, acids, and salts present on and around the underarm skin causes magnesium ions to be released and available for absorption into the skin
Implementation Method 2
a magnesium compound (such as magnesium hydroxide, magnesium oxide, magnesium sulfate, magnesium chloride, or a combination thereof) is used alone or in combination with one or more ingredients that increase permeation of magnesium ions into the underarm skin
Data Source
AI summary
A roll-on product, including magnesium hydroxide; propanediol; glycerin and glycine soja (soybean), is advantageously used as a deodorant and/or for transdermal magnesium delivery to the human body. Combinations of a magnesium source (especially magnesium hydroxide), with propanediol, and with glycerin and glycine soja (soybean) are advantageous for transdermal delivery of magnesium to the body via a roll-on product, a stick, a spray, a lotion, etc. Magnesium deficiency is addressed via products easily used by an ordinary consumer for dermal application.