Transdermal Patch Protective Film Segmentation

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Solution Overview

Problem

Transdermal therapeutic systems are difficult to apply, especially for individuals with limited motor function, due to challenges in removing the protective film without touching the active ingredient region, leading to contamination risks.

Innovation Solution

A transdermal therapeutic system design featuring a protective film with two parts having different physical properties, such as surface tension, thickness, stiffness, and surface structure, allowing for easier removal by differing adhesion strengths and take-off efficiencies, and visual differentiation for easier handling.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If the protective film is made as a single piece covering the entire application face, then the active ingredient is well protected from contamination, but the protective film becomes difficult to remove without touching the active ingredient region

Engineering Contradiction:
Improvecontamination preventionVSAvoidprotective film removal
Core Design Contradiction:
ReliabilityVSEase of operation

Solution Approach 1:

The protective film is divided into two separate parts: a first protective film part that covers the active ingredient depot and a second protective film part that covers the application face. This segmentation allows the second part to be removed first for easy gripping, while the first part remains to protect the active ingredient, thus resolving the contradiction between ease of removal and contamination prevention.

Inventive Principle:
Principle #1Segmentation

2Ease of operation

If the protective film projects beyond the edge of the patch for better gripping, then removal is facilitated, but the risk of contaminating the fingers increases

Engineering Contradiction:
Improvegripping facilitationVSAvoidcontamination risk
Core Design Contradiction:
Ease of operationVSObject-affected harmful factors

Solution Approach 1:

By dividing the protective film into two parts with different extents of projection, the second protective film part can project beyond the patch edge to facilitate gripping, while the first protective film part covering the active ingredient does not necessarily project as far, thus minimizing contamination risk while maintaining ease of removal.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The second protective film part is designed to be removable first and serves as a preliminary action that exposes the first protective film part. This allows users to grip and remove the second part without risking contamination of the active ingredient region, as the first part remains in place as a protective barrier.

Inventive Principle:
Principle #10Preliminary action

3Object-affected harmful factors

If a two-part protective film is used with one part removable first, then contamination risk is reduced, but the device complexity increases

Engineering Contradiction:
Improvecontamination risk reductionVSAvoidprotective film structure
Core Design Contradiction:
Object-affected harmful factorsVSDevice complexity

Solution Approach 1:

The protective film is segmented into two parts that can be produced as a single laminated structure during manufacturing. This segmentation provides the functional benefits of reduced contamination risk while maintaining relatively simple manufacturing processes, thus balancing contamination prevention with device complexity.

Inventive Principle:
Principle #1Segmentation

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Enables easier and safer application of transdermal therapeutic systems, reducing contamination risks and improving handling for individuals with limited motor capabilities by facilitating the removal of the protective film without touching the active ingredient area.

Implementation Method 1

the different physical properties include different surface tensions of the protective film parts on the sides facing the application face, as a result of which different strengths of adhesion of the protective film parts to the application face is achieved

Methodology Applied
Scientific EffectSurface tension: Surface Tension

Implementation Method 2

an application face which is designed for application to a skin and which is adhesive on at least some parts of the surface

Methodology Applied
Scientific EffectAdhesion: Adhesive

Data Source

PatentUS9439873B2Application aid
Publication Date: 2016.09.13 LUYE PHARMA AG
  • US9439873B2 patent drawing
  • US9439873B2 patent drawing
  • US9439873B2 patent drawing

AI summary

The invention relates to a transdermal therapeutic system (10) comprising an active ingredient depot (11) that contains at least one active ingredient, comprising an application face which is designed for applying on a skin and which is adhesive on at least some parts of the surface, and comprising a protective film (14) which covers the application face and which comprises a first protective film part (14a) and a second protective film part (14b). The first protective film part (14a) differs from the second protective film part (14b) in terms of physical properties.