Transgenic Biomass Composition for Higher Sugar Conversion

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Solution Overview

Problem

The existing methods for converting plant biomass into biofuels and chemical intermediates are limited by the recalcitrance of the lignocellulose matrix, leading to inefficient conversion of solar energy stored in plants into usable forms.

Innovation Solution

Introducing exogenous nucleic acids into plant cells of species like sorghum, Miscanthus, and sugarcane to alter biomass composition, enhancing sugar content, availability, and conversion efficiency through regulatory regions linked to specific polypeptides or inhibiting endogenous nucleic acids, thereby improving the processing efficiency of plant materials.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of manufacture

If direct combustion or conventional biochemical processes are used to convert plant biomass into energy or biofuels, then the process is relatively simple, but the conversion efficiency of solar energy stored in plants is very low

Engineering Contradiction:
Improveprocess simplicityVSAvoidconversion efficiency
Core Design Contradiction:
Ease of manufactureVSProductivity

Solution Approach 1:

The patent modifies the chemical composition parameters of plant biomass by altering lignin content, cellulose content, and sugar composition through genetic engineering. These parameter changes make the biomass more suitable for efficient conversion processes, thereby improving conversion efficiency without significantly complicating the manufacturing process

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent performs preliminary modification of the biomass composition before the actual energy conversion process. By pre-altering the lignocellulose structure and increasing sugar content through genetic engineering, the biomass is prepared in advance to enable more efficient conversion, avoiding the need for complex pretreatment steps during the conversion process itself

Inventive Principle:
Principle #10Preliminary action

2Stability of the object's composition

If the lignocellulose matrix structure is maintained in conventional plants, then the plant structure is stable, but the recalcitrance of the matrix limits conversion efficiency

Engineering Contradiction:
Improveplant structure stabilityVSAvoidconversion efficiency
Core Design Contradiction:
Stability of the object's compositionVSProductivity

Solution Approach 1:

The patent applies local quality changes by specifically modifying certain components of the lignocellulose matrix (such as reducing lignin content or altering hemicellulose composition) while maintaining the overall structural integrity of the plant. This localized modification improves conversion efficiency in specific regions of the biomass without compromising the overall structural stability of the plant

Inventive Principle:
Principle #3Local quality

3Device complexity

If only small fractions of solar energy are converted into biofuels through conventional processes, then the existing industrial processes are simple, but the amount of liquid transportation fuel obtained is limited

Engineering Contradiction:
Improveindustrial process complexityVSAvoidamount of biofuel produced
Core Design Contradiction:
Device complexityVSQuantity of substance

Solution Approach 1:

The patent creates transgenic plant copies that inherit modified genetic traits for improved biomass composition. By propagating these genetically modified plants, the system produces large quantities of biomass with enhanced conversion properties, thereby increasing the total amount of biofuel that can be produced without proportionally increasing process complexity

Inventive Principle:
Principle #26Copying

Data Source

PatentUS12584142B2Transgenic plants having altered biomass composition
Publication Date: 2026.03.24 CERES INC
  • US12584142B2 patent drawing
  • US12584142B2 patent drawing
  • US12584142B2 patent drawing

AI summary

Methods and materials for modulating biomass composition in plants are disclosed. For example, nucleic acids encoding biomass composition-modulating polypeptides are disclosed as well as methods for using such nucleic acids to transform plant cells. Also disclosed are plants having altered biomass composition and plant products produced from plants having altered biomass composition.