Transistor Sensor Virus Detection Device
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Solution Overview
Problem
Current virus detection methods for coronaviruses and influenza viruses are complex, time-consuming, and lack sensitivity, leading to difficulties in accurate differentiation and rapid screening, especially during peak seasons.
Innovation Solution
A detection device and method utilizing a detection module with transistor sensors integrated with biorecognition molecules on a substrate, capable of real-time detection of viruses by measuring electrical signal responses, allowing for rapid and accurate identification of coronaviruses and influenza viruses in single, hybrid, or mixed samples.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Measurement precision
If nucleic acid detection is used to detect coronaviruses, then detection accuracy is improved, but detection time increases to at least 2 hours and device complexity increases
Solution Approach 1:
The patent replaces the mechanical/nucleic acid-based detection system with an electronic transistor sensor system. The transistor sensor directly detects viral proteins or antibodies through electrical signal changes, eliminating the need for complex nucleic acid extraction and amplification processes. This substitution reduces detection time from hours to minutes while maintaining high detection accuracy through sensitive electrical measurements.
Solution Approach 2:
The patent changes the detection parameter from nucleic acid concentration to electrical signal response. By measuring changes in electrical current or resistance when viral proteins bind to the transistor sensor surface, the system achieves rapid detection without the time-consuming nucleic acid amplification steps, thus reducing detection time while preserving accuracy.
2Ease of operation
If kit detection is used to detect antibodies, then operation is simplified, but sensitivity decreases and detection accuracy worsens
Solution Approach 1:
The patent replaces the traditional immunoassay kit with an electronic transistor sensor system. The transistor sensor provides automated electrical signal measurement and processing, maintaining ease of operation while significantly improving sensitivity through precise electrical detection of protein-antibody interactions, eliminating the need for manual colorimetric readings.
Solution Approach 2:
The patent employs composite material structures combining biorecognition elements (antibodies or antigens) with transistor sensor materials. This composite approach enables the sensor to maintain operational simplicity while achieving high detection sensitivity through the synergistic combination of specific biological recognition and sensitive electrical transduction.
3Adaptability or versatility
If current detection methods are used for hybrid and mixed samples, then detection capability is limited, but device complexity and operation complexity increase
Solution Approach 1:
The patent designs the transistor sensor with universal detection capability that can detect different viral targets (coronavirus, influenza virus) and different sample types (single sample, hybrid sample, mixed sample) using the same detection platform. The sensor's electrical measurement approach is universally applicable to various analytes, enabling multi-functional detection without increasing device complexity.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The method achieves a detection time of 1 minute with improved sensitivity and accuracy, enabling efficient large-scale screening and potential social and economic benefits.
Implementation Method 1
Each transistor sensor unit is modified with different biorecognition molecules and is integrated in the same sample cell
Implementation Method 2
measuring electrical signal responses, allowing for rapid and accurate identification of coronaviruses and influenza viruses
Data Source
AI summary
The present application is related to a detection device and method for coronavirus and influenza virus. The device comprises a detection module (20), a signal processing circuit (30), a controller (40), a displayer (50), a digital-to-analog conversion circuit (60), and a clock (70). Noticeably, the detection module (20) comprises a sample cell, and a transistor sensor combination integrated in the sample cell and used for measuring different targets. The detection module (20) may comprise a sample cell array to realize simultaneous detection of a plurality of samples to be detected. The detection method comprises the following steps: adding a sample to be detected into a sample cell, reading an electrical signal response of each transistor sensor in the sample cell to judge whether the sample to be detected contains a virus to be detected or not. The present application belongs to the technical field of biological detection.